RegulonDB RegulonDB 10.8: Gene Form
   

actP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

acs actP yjcF yjcH actPp actPp yjcFp6 yjcFp6

Gene      
Name: actP    Texpresso search in the literature
Synonym(s): ECK4060, EG11942, b4067, yjcG
Genome position(nucleotides): 4283253 <-- 4284902 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.76
Reference(s): [1] Gimenez R., et al., 2003
External database links:  
ASAP:
ABE-0013328
ECHOBASE:
EB1886
OU-MICROARRAY:
b4067
PortEco:
actP
STRING:
511145.b4067
COLOMBOS: actP


Product      
Name: acetate/glycolate:cation symporter
Synonym(s): ActP, YjcG
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 59.197
Isoelectric point: 9.75
Motif(s):
 
Type Positions Sequence
146 -> 168 IRILSACGSLVVVALYLIAQMVG
212 -> 234 AVLLLFGASFMAFMVMKHVGFSF
183 -> 205 IAVVLVGVLMMMYVLFGGMLATT
63 -> 468 YYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLG
261 -> 283 PISALSLGLGLMFGTAGLPHILM

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0022857 - transmembrane transporter activity
GO:0015123 - acetate transmembrane transporter activity
GO:0043879 - glycolate transmembrane transporter activity
GO:0015654 - tellurite transmembrane transporter activity
biological_process GO:0006811 - ion transport
GO:0006814 - sodium ion transport
GO:0055085 - transmembrane transport
GO:0006847 - plasma membrane acetate transport
GO:0097339 - glycolate transmembrane transport
GO:0015710 - tellurite transport
External database links:  
DIP:
DIP-12552N
ECOCYC:
YJCG-MONOMER
ECOLIWIKI:
b4067
INTERPRO:
IPR014083
INTERPRO:
IPR038377
INTERPRO:
IPR018212
INTERPRO:
IPR001734
MINT:
MINT-1259884
PANTHER:
PTHR11819
PFAM:
PF00474
PRIDE:
P32705
PRODB:
PRO_000022053
PROSITE:
PS00457
PROSITE:
PS50283
PROSITE:
PS00456
REFSEQ:
NP_418491
UNIPROT:
P32705


Operon      
Name: acs-yjcH-actP         
Operon arrangement:
Transcription unit        Promoter
actP
acs-yjcHG
acs-yjcHG


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: IHF, Fis


Regulation by small RNA    
  Display Regulation
small RNA omrA, omrB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yjcFp6 4283106 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Gimenez R., Nunez MF., Badia J., Aguilar J., Baldoma L., 2003, The gene yjcG, cotranscribed with the gene acs, encodes an acetate permease in Escherichia coli., J Bacteriol 185(21):6448-55

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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