RegulonDB RegulonDB 10.9: Gene Form
   

flgK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

flgK flgL flgJ TSS_1351 TSS_1351 TSS_1350 TSS_1350 TSS_1349 TSS_1349 TSS_1348 TSS_1348 flgKp flgKp TSS_1347 TSS_1347

Gene      
Name: flgK    Texpresso search in the literature
Synonym(s): ECK1067, EG11967, b1082, flaS
Genome position(nucleotides): 1138378 --> 1140021 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.82
External database links:  
ASAP:
ABE-0003660
CGSC:
758
ECHOBASE:
EB1910
ECOLIHUB:
flgK
OU-MICROARRAY:
b1082
STRING:
511145.b1082
COLOMBOS: flgK


Product      
Name: flagellar hook-filament junction protein 1
Synonym(s): FlaS, FlgK
Sequence: Get amino acid sequence Fasta Format
Cellular location: extracellular space,cell projection
Molecular weight: 57.93
Isoelectric point: 4.253
Motif(s):
 
Type Positions Sequence
5 -> 35 INNAMSGLNAAQAALNTASNNISSYNVAGYT
491 -> 546 ATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI
2 -> 547 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.12 - flagellum
  2 - information transfer --> 2.3 - protein related --> 2.3.4 - chaperoning, repair (refolding)
  5 - cell processes --> 5.3 - motility, chemotaxis, energytaxis (aerotaxis, redoxtaxis etc)
  6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)  
cellular_component GO:0005576 - extracellular region
GO:0009288 - bacterial-type flagellum
GO:0009424 - bacterial-type flagellum hook
molecular_function GO:0005198 - structural molecule activity
GO:0005515 - protein binding
biological_process GO:0071973 - bacterial-type flagellum-dependent cell motility
GO:0044780 - bacterial-type flagellum assembly
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-9639N
ECOCYC:
EG11967-MONOMER
ECOLIWIKI:
b1082
INTERPRO:
IPR001444
INTERPRO:
IPR002371
INTERPRO:
IPR010930
PANTHER:
PTHR30033
PFAM:
PF06429
PFAM:
PF00460
PRIDE:
P33235
PRINTS:
PR01005
PRODB:
PRO_000022646
REFSEQ:
NP_415600
SMR:
P33235
UNIPROT:
P33235


Operon      
Name: flgKL         
Operon arrangement:
Transcription unit        Promoter
flgK


Transcriptional Regulation      
Display Regulation             
Activated by: FlhDC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1347 1137587 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1348 1138353 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1349 1140510 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1350 1140515 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1351 1140518 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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