RegulonDB RegulonDB 11.1: Gene Form
   

wbbJ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

wbbH wbbK wbbI insH7 wbbJ terminator TSS_2387 TSS_2387 TSS_2386 TSS_2386 TSS_2385 TSS_2385 TSS_2384 TSS_2384 TSS_2383 TSS_2383 wbbKp4 wbbKp4 TSS_2382 TSS_2382 TSS_2381 TSS_2381 insHp4 insHp4 insHp5 insHp5 insHp6 insHp6 TSS_2380 (cluster) TSS_2380 (cluster) TSS_2379 TSS_2379

Gene      
Name: wbbJ    Texpresso search in the literature
Synonym(s): ECK2027, EG11984, b2033, yefH
Genome position(nucleotides): 2104494 <-- 2105084
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 40.61
External database links:  
ASAP:
 ABE-0006749
ECHOBASE:
 EB1927
ECOLIHUB:
 wbbJ
OU-MICROARRAY:
 b2033
STRING:
 511145.b2033
COLOMBOS: wbbJ


Product      
Name: putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ
Synonym(s): WbbJ, YefH
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 21.675
Isoelectric point: 9.94
Motif(s):
 
Type Positions Sequence Comment
133 -> 167 VVIGQRVWLGENVTVLPGTIIGNGVVVGANSVVRG
168 -> 176 SIPENTVIA UniProt: In Ref. 1; AAC31635..
187 -> 189 NHE UniProt: In Ref. 1; AAC31635..

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016740 - transferase activity
GO:0016746 - acyltransferase activity
GO:0008374 - O-acyltransferase activity
biological_process GO:0009103 - lipopolysaccharide biosynthetic process
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P37750
DIP:
 DIP-11115N
ECOCYC:
 EG11984-MONOMER
ECOLIWIKI:
 b2033
INTERPRO:
 IPR001451
INTERPRO:
 IPR011004
MODBASE:
 P37750
PFAM:
 PF00132
PRIDE:
 P37750
REFSEQ:
 NP_416537
SMR:
 P37750
SWISSMODEL:
 P37750
UNIPROT:
 P37750


Operon      
Name: wbbIJK         
Operon arrangement:
Transcription unit        Promoter
wbbIJK


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2379 2102902 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2380 (cluster) 2102949 reverse nd [RS-EPT-CBR] [1]
  promoter insHp6 2103049 reverse nd [COMP-AINF] [2]
  promoter insHp5 2103090 reverse nd [COMP-AINF] [2]
  promoter insHp4 2103093 reverse nd [COMP-AINF] [2]
  promoter TSS_2381 2103462 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2382 2103479 reverse nd [RS-EPT-CBR] [1]
  promoter wbbKp4 2104606 reverse nd [COMP-AINF] [2]
  promoter TSS_2383 2105007 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2384 2105046 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2385 2105457 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2386 2106618 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2387 2106661 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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