RegulonDB RegulonDB 10.9: Gene Form
   

btsS gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

btsS mlrA btsR yehS FliZ yohOp6 yohOp6 mlrAp mlrAp mlrAp9 mlrAp9 mlrAp6 mlrAp6 TSS_2443 TSS_2443 TSS_2442 TSS_2442

Gene      
Name: btsS    Texpresso search in the literature
Synonym(s): ECK2118, EG12007, b2126, yehU
Genome position(nucleotides): 2212959 <-- 2214644 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.59
External database links:  
ASAP:
ABE-0007027
ECHOBASE:
EB1945
ECOLIHUB:
yehU
OU-MICROARRAY:
b2126
STRING:
511145.b2126
COLOMBOS: btsS


Product      
Name: high-affinity pyruvate receptor
Synonym(s): BtsS, YehU
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 62.092
Isoelectric point: 8.609
Motif(s):
 
Type Positions Sequence
4 -> 24 FNLVLLLLQQMCVFLVIAWLM
28 -> 196 PLFIPLMQVTVRLPHKFLCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSMGGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILAIARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLD
141 -> 161 ITAGAVTFVAEMVQMLIILAI
44 -> 64 FLCYIVFSIFCIMGTWFGLHI
175 -> 176 IA

 

Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.3 - protein related --> 2.3.3 - posttranslational modification
  3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level --> 3.1.2.4 - complex regulation --> 3.1.2.4.3 - two component regulatory systems (external signal)
  3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional --> 3.1.3.2 - covalent modification, demodification, maturation
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0016301 - kinase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0000155 - phosphorelay sensor kinase activity
GO:0004673 - protein histidine kinase activity
GO:0033293 - monocarboxylic acid binding
biological_process GO:0016310 - phosphorylation
GO:0000160 - phosphorelay signal transduction system
GO:0031667 - response to nutrient levels
GO:0018106 - peptidyl-histidine phosphorylation
GO:0071555 - cell wall organization
GO:0023014 - signal transduction by protein phosphorylation
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-11909N
ECOCYC:
EG12007-MONOMER
ECOLIWIKI:
b2126
INTERPRO:
IPR003018
INTERPRO:
IPR010559
INTERPRO:
IPR011620
INTERPRO:
IPR036890
MODBASE:
P0AD14
PFAM:
PF07694
PFAM:
PF06580
PRIDE:
P0AD14
REFSEQ:
NP_416630
SMART:
SM00065
SMR:
P0AD14
UNIPROT:
P0AD14


Operon      
Name: btsSR         
Operon arrangement:
Transcription unit        Promoter
btsSR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2442 2212969 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2443 2214673 reverse nd [RS-EPT-CBR] [1]
  promoter mlrAp6 2214749 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter mlrAp9 2214785 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter yohOp6 2215586 forward Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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