Gene
Name:	pbpG
Synonym(s):	ECK2127, EG12015, b2134, yohB
Genome position(nucleotides):	2223938 <-- 2224870
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.7
External database links:

ASAP:	ABE-0007050
CGSC:	36349
ECHOBASE:	EB1952
ECOLIHUB:	pbpG
OU-MICROARRAY:	b2134
STRING:	511145.b2134
COLOMBOS:	pbpG

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_2451	2223795	forward	nd	[RS-EPT-CBR]	[9]
promoter	pbpGp7	2224941	reverse	nd	[COMP-AINF]	[10]
promoter	pbpGp5	2225066	reverse	nd	[COMP-AINF]	[10]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[COMP-AINF] Inferred computationally without human oversight

Reference(s)
[1] Denome SA., Elf PK., Henderson TA., Nelson DE., Young KD., 1999, Escherichia coli mutants lacking all possible combinations of eight penicillin binding proteins: viability, characteristics, and implications for peptidoglycan synthesis., J Bacteriol 181(13):3981-93
[2] Fischer E., 1989, Osmolability of Escherichia coli and modification of [125I]ampicillin-binding by competence induction for uptake of transforming DNA., Arch Microbiol 153(1):43-6
[3] Henderson TA., Young KD., Denome SA., Elf PK., 1997, AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli., J Bacteriol 179(19):6112-21
[4] Jacoby GH., Young KD., 1988, Unequal distribution of penicillin-binding proteins among inner membrane vesicles of Escherichia coli., J Bacteriol 170(8):3660-7
[5] Leidenix MJ., Jacoby GH., Henderson TA., Young KD., 1989, Separation of Escherichia coli penicillin-binding proteins into different membrane vesicles by agarose electrophoresis and sizing chromatography., J Bacteriol 171(10):5680-6
[6] Romeis T., Holtje JV., 1994, Specific interaction of penicillin-binding proteins 3 and 7/8 with soluble lytic transglycosylase in Escherichia coli., J Biol Chem 269(34):21603-7
[7] Satta G., Cornaglia G., Mazzariol A., Golini G., Valisena S., Fontana R., 1995, Target for bacteriostatic and bactericidal activities of beta-lactam antibiotics against Escherichia coli resides in different penicillin-binding proteins., Antimicrob Agents Chemother 39(4):812-8
[8] Voedts H., Dorchene D., Lodge A., Vollmer W., Arthur M., Hugonnet JE., 2021, Role of endopeptidases in peptidoglycan synthesis mediated by alternative cross-linking enzymes in Escherichia coli., EMBO J 40(19):e108126
[9] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[10] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

RNA cis-regulatory element

Attenuation:	Translational