RegulonDB RegulonDB 10.9: Gene Form
   

sdaC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

sdaB ppnN sdaC ygdGp2 ygdGp2 sdaCp sdaCp TSS_3114 TSS_3114 TSS_3113 TSS_3113

Gene      
Name: sdaC    Texpresso search in the literature
Synonym(s): ECK2791, EG12142, b2796, dcrA
Genome position(nucleotides): 2928229 --> 2929518 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.33
External database links:  
ASAP:
ABE-0009169
CGSC:
33329
ECHOBASE:
EB2063
ECOLIHUB:
sdaC
OU-MICROARRAY:
b2796
STRING:
511145.b2796
COLOMBOS: sdaC


Product      
Name: L-serine:H+ symporter SdaC
Synonym(s): DcrA, SdaC
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 46.906
Isoelectric point: 9.545
Motif(s):
 
Type Positions Sequence
47 -> 67 VGGMIPLIIMAILAFPMTFFA
202 -> 222 ATGNGLWMTLWLAIPVMVFSF
348 -> 368 LNRITALFMLVTTWIVATLNP
298 -> 318 APVIAWMAPIIAIIAITKSFL
100 -> 120 LITLLYFFAIYPILLVYSVAI

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.11 - serine
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015171 - amino acid transmembrane transporter activity
GO:0015194 - L-serine transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0003333 - amino acid transmembrane transport
GO:0015825 - L-serine transport
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
SDAC-MONOMER
ECOLIWIKI:
b2796
INTERPRO:
IPR004694
PRIDE:
P0AAD6
PRODB:
PRO_000023917
REFSEQ:
NP_417276
UNIPROT:
P0AAD6


Operon      
Name: sdaCB         
Operon arrangement:
Transcription unit        Promoter
sdaCB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3113 2926407 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3114 2926537 forward nd [RS-EPT-CBR] [1]
  promoter sdaCp 2928035 forward A σ32-dependent
Read more >
[AIPP], [ICWHO] [2]
  promoter ygdGp2 2930873 forward Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [AIPP] Automated inference of promoter position

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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