RegulonDB RegulonDB 10.8: Gene Form
   

brnQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

proY brnQ phoR terminator anti-terminator anti-anti-terminator TSS_507 TSS_507 TSS_506 TSS_506 TSS_505 TSS_505 TSS_504 (cluster) TSS_504 (cluster) TSS_503 TSS_503 brnQp brnQp TSS_502 TSS_502

Gene      
Name: brnQ    Texpresso search in the literature
Synonym(s): ECK0395, EG12168, b0401, hrbA
Genome position(nucleotides): 419591 --> 420910 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.61
External database links:  
ASAP:
 ABE-0001394
CGSC:
 950
ECHOBASE:
 EB2087
OU-MICROARRAY:
 b0401
PortEco:
 brnQ
STRING:
 511145.b0401
COLOMBOS: brnQ


Product      
Name: branched chain amino acid transporter BrnQ
Synonym(s): BrnQ, BrnQ branched chain amino acid LIVCS transporter, HrbA, LIV-II
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 46.209
Isoelectric point: 8.448
Motif(s):
 
Type Positions Sequence
339 -> 359 ISVPVLTAIYPPCIALVVLSF
370 -> 390 VIAPPMFISLLFGILDGIKAS
150 -> 170 FLAPLKIIALVILSVAAIVWP
10 -> 30 IIALGFMTFALFVGAGNIIFP
278 -> 298 GGSFLLAALIFIACLVTAVGL

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.3 - amino acids
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.18 - isoleucine/valine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.19 - leucine
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0015658 - branched-chain amino acid transmembrane transporter activity
GO:0005304 - L-valine transmembrane transporter activity
GO:0015190 - L-leucine transmembrane transporter activity
GO:0015188 - L-isoleucine transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0015803 - branched-chain amino acid transport
GO:0015820 - leucine transport
GO:0015829 - valine transport
GO:0015818 - isoleucine transport
GO:1902475 - L-alpha-amino acid transmembrane transport
GO:0098655 - cation transmembrane transport
GO:1903785 - L-valine transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-48078N
ECOCYC:
 BRNQ-MONOMER
ECOLIWIKI:
 b0401
INTERPRO:
 IPR004685
MINT:
 MINT-1238115
PANTHER:
 PTHR30588
PFAM:
 PF05525
PRIDE:
 P0AD99
PRODB:
 PRO_000022231
REFSEQ:
 NP_414935
UNIPROT:
 P0AD99


Operon      
Name: brnQ-proY         
Operon arrangement:
Transcription unit        Promoter
brnQ-proY


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_502 419419 forward nd [RS-EPT-CBR] [1]
  promoter TSS_503 419509 forward nd [RS-EPT-CBR] [1]
  promoter TSS_504 (cluster) 419551 forward For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_505 419559 forward nd [RS-EPT-CBR] [1]
  promoter TSS_506 419571 forward nd [RS-EPT-CBR] [1]
  promoter TSS_507 420215 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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