RegulonDB RegulonDB 11.0: Gene Form
   

coaE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

zapD coaE yacG b0100 yacM TSS_229 TSS_229 TSS_228 TSS_228 TSS_227 TSS_227 TSS_226 TSS_226 TSS_225 TSS_225 TSS_224 TSS_224 TSS_223 TSS_223 TSS_222 TSS_222

Gene      
Name: coaE    Texpresso search in the literature
Synonym(s): ECK0103, EG12312, b0103, yacE
Genome position(nucleotides): 112599 <-- 113219
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.66
External database links:  
ASAP:
 ABE-0000357
ECHOBASE:
 EB2218
ECOLIHUB:
 coaE
OU-MICROARRAY:
 b0103
STRING:
 511145.b0103
COLOMBOS: coaE


Product      
Name: dephospho-CoA kinase
Synonym(s): CoaE, YacE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 22.622
Isoelectric point: 6.148
Motif(s):
 
Type Positions Sequence Comment
3 -> 177 YIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNG
4 -> 200 IVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQF UniProt: DPCK.
12 -> 17 GSGKST UniProt: ATP.
72 -> 74 ERI UniProt: In Ref. 1..
86 -> 86 A UniProt: In Ref. 1..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.5 - Coenzyme A and its modification
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016740 - transferase activity
GO:0016301 - kinase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0004140 - dephospho-CoA kinase activity
biological_process GO:0015937 - coenzyme A biosynthetic process
GO:0016310 - phosphorylation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0A6I9
DIP:
 DIP-47935N
ECOCYC:
 EG12312-MONOMER
ECOLIWIKI:
 b0103
INTERPRO:
 IPR001977
INTERPRO:
 IPR027417
MODBASE:
 P0A6I9
PDB:
 1N3B
PDB:
 1T3H
PDB:
 1VHL
PDB:
 1VHT
PDB:
 1VIY
PDB:
 6ARI
PFAM:
 PF01121
PRIDE:
 P0A6I9
PRODB:
 PRO_000022311
PROSITE:
 PS51219
REFSEQ:
 NP_414645
SMR:
 P0A6I9
UNIPROT:
 P0A6I9


Operon      
Name: coaE-zapD-yacG         
Operon arrangement:
Transcription unit        Promoter
yacG
coaE-zapD-yacG


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_222 112251 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_223 112273 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_224 112599 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_225 112607 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_226 112609 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_227 112617 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_228 112696 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_229 112703 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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