RegulonDB RegulonDB 11.0: Gene Form
   

afuC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

afuC mmuM insB2 insAB2 afuB insA2 mmuP

Gene      
Name: afuC    Texpresso search in the literature
Synonym(s): ECK0264, EG12340, b0262, fbpC, yagC
Genome position(nucleotides): 277756 <-- 278802
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.35
External database links:  
ASAP:
ABE-0000898
ECHOBASE:
EB2244
ECOLIHUB:
afuC
OU-MICROARRAY:
b0262
STRING:
511145.b0262
COLOMBOS: afuC


Product      
Name: CP4-6 prophage; ABC transporter ATP-binding protein AfuC
Synonym(s): AfuC, FbpC, YagC
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 39.059
Isoelectric point: 6.046
Motif(s):
 
Type Positions Sequence Comment
7 -> 237 VELRNVTKRFGSNTVIDNINLTIPQGQMVTLLGPSGCGKTTILRLVAGLEKPSEGQIFIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGENVGYGLKMLGVPRAELKARVKEALAMVDLEGFEDRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMRDKIRELQKQFDITSLYVTHDQSEAFAVSDTVLVMNKGHIMQIGSPQDLYRQPASRFMASFM UniProt: ABC transporter.
23 -> 164 DNINLTIPQGQMVTLLGPSGCGKTTILRLVAGLEKPSEGQIFIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGENVGYGLKMLGVPRAELKARVKEALAMVDLEGFEDRFVDQISGGQQQRVALARALILKPKVLLFDEPL
39 -> 46 GPSGCGKT UniProt: ATP.
273 -> 344 VGVRPEAITLSDRGEESQRCVIRHVAYMGPQYEVTVEWHGQEILLQVNATRLQPDVGEQYYLEIHPYGMFVL

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
molecular_function GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0022857 - transmembrane transporter activity
GO:0015408 - ABC-type ferric iron transporter activity
biological_process GO:0006811 - ion transport
GO:0055072 - iron ion homeostasis
GO:0055085 - transmembrane transport
GO:0034755 - iron ion transmembrane transport
Note(s): Note(s): ...[more].
Evidence: [AIFS] Automated inference of function from sequence
Reference(s): [1] Riley M., et al., 2006
External database links:  
ALPHAFOLD:
P37009
DIP:
DIP-9064N
ECOCYC:
YAGC-MONOMER
ECOLIWIKI:
b0262
INTERPRO:
IPR013611
INTERPRO:
IPR015853
INTERPRO:
IPR027417
INTERPRO:
IPR017871
INTERPRO:
IPR003439
INTERPRO:
IPR003593
INTERPRO:
IPR030287
INTERPRO:
IPR008995
MODBASE:
P37009
PANTHER:
PTHR24220:SF675
PFAM:
PF08402
PFAM:
PF00005
PRIDE:
P37009
PRODB:
PRO_000022577
PROSITE:
PS50893
PROSITE:
PS00211
PROSITE:
PS51242
REFSEQ:
NP_414796
SMART:
SM00382
SMR:
P37009
SWISSMODEL:
P37009
UNIPROT:
P37009


Operon      
Name: insAB2A2B2-afuBC         
Operon arrangement:
Transcription unit        Promoter
insA2B2AB2-afuBC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Riley M., Abe T., Arnaud MB., Berlyn MK., Blattner FR., Chaudhuri RR., Glasner JD., Horiuchi T., Keseler IM., Kosuge T., Mori H., Perna NT., Plunkett G., Rudd KE., Serres MH., Thomas GH., Thomson NR., Wishart D., Wanner BL., 2006, Escherichia coli K-12: a cooperatively developed annotation snapshot--2005., Nucleic Acids Res 34(1):1-9


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