RegulonDB RegulonDB 10.8: Gene Form
   

kduD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

araE kduI kduD CRP AraC AraC anti-anti-terminator anti-terminator terminator anti-anti-terminator anti-terminator araEp araEp ygeAp5 ygeAp5

Gene      
Name: kduD    Texpresso search in the literature
Synonym(s): ECK2840, EG12361, b2842, ygeC, yqeD
Genome position(nucleotides): 2982497 <-- 2983258 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.97
External database links:  
ASAP:
 ABE-0009330
ECHOBASE:
 EB2264
OU-MICROARRAY:
 b2842
PortEco:
 kduD
STRING:
 511145.b2842
COLOMBOS: kduD


Product      
Name: putative 2-keto-3-deoxy-D-gluconate dehydrogenase
Synonym(s): KduD, YgeC, YqeD
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 27.07
Isoelectric point: 5.054
Motif(s):
 
Type Positions Sequence
20 -> 250 TGLGQGMALGLAQAGCDIVGINIVEPTETIEQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRWGLPSDLMGPIVFLASSASDYVNGYTIAVDGGW
14 -> 38 VVTGCDTGLGQGMALGLAQAGCDIV

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.1 - unassigned reversible reactions
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016491 - oxidoreductase activity
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0008678 - 2-deoxy-D-gluconate 3-dehydrogenase activity
GO:0033764 - steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 - NAD binding
GO:0047001 - 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity
biological_process GO:0019698 - D-galacturonate catabolic process
GO:0042840 - D-glucuronate catabolic process
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 KDUD-MONOMER
ECOLIWIKI:
 b2842
INTERPRO:
 IPR020904
INTERPRO:
 IPR002347
INTERPRO:
 IPR011286
INTERPRO:
 IPR036291
MODBASE:
 P37769
PANTHER:
 PTHR24322:SF716
PFAM:
 PF13561
PRIDE:
 P37769
PRINTS:
 PR00081
PRINTS:
 PR00080
PRODB:
 PRO_000023058
PROSITE:
 PS00061
REFSEQ:
 NP_417319
SMR:
 P37769
UNIPROT:
 P37769


Operon      
Name: kduD         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ygeAp5 2980803 reverse Similarity to the consensus
Read more > 		[ICWHO] [1]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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