RegulonDB RegulonDB 11.1: Gene Form
   

yfeH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ligA yfeH yfeR ypeB yfeRp1 yfeRp1 yfeHp3 yfeHp3 TSS_2688 TSS_2688 yfeHp5 yfeHp5

Gene      
Name: yfeH    Texpresso search in the literature
Synonym(s): ECK2404, EG12376, b2410
Genome position(nucleotides): 2526946 --> 2527944
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.75
External database links:  
ASAP:
 ABE-0007936
ECHOBASE:
 EB2279
ECOLIHUB:
 yfeH
OU-MICROARRAY:
 b2410
STRING:
 511145.b2410
COLOMBOS: yfeH


Product      
Name: putative solute:Na+ symporter
Synonym(s): YfeH
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 36.406
Isoelectric point: 9.94
Motif(s):
 
Type Positions Sequence Comment
8 -> 316 DPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIALLFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGFLYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGSLEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVNGIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLSFNKADEITIVFCGSKKSLANGIPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKR
325 -> 332 QESSADKA UniProt: In Ref. 4; M24278..

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.9.B - Putative uncharacterized transport protein
Gene Ontology Terms (GO)  
cellular_component GO:0005886 - plasma membrane
molecular_function GO:0015293 - symporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P39836
ECOCYC:
 EG12376-MONOMER
ECOLIWIKI:
 b2410
INTERPRO:
 IPR016833
INTERPRO:
 IPR038770
PANTHER:
 PTHR18640
PFAM:
 PF13593
PRIDE:
 P39836
REFSEQ:
 NP_416905
UNIPROT:
 P39836


Operon      
Name: yfeH         
Operon arrangement:
Transcription unit        Promoter
yfeH


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yfeHp5 2526909 forward nd [COMP-AINF] [2]
  promoter TSS_2688 2526926 forward nd [RS-EPT-CBR] [3]
  promoter yfeHp3 2526933 forward nd [COMP-AINF] [2]
  promoter yfeRp1 2527039 reverse nd [COMP-AINF] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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