RegulonDB RegulonDB 11.1: Gene Form
   

dgoK gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dgoD dgoK dgoR yidX dgoA CRP DgoR DgoR TSS_4257 TSS_4257 dgoRp dgoRp

Gene      
Name: dgoK    Texpresso search in the literature
Synonym(s): ECK3686, EG20051, b3693, yidV
Genome position(nucleotides): 3873596 <-- 3874474
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.15
External database links:  
ASAP:
 ABE-0012076
CGSC:
 858
ECHOBASE:
 EB1668
ECOLIHUB:
 dgoK
OU-MICROARRAY:
 b3693
STRING:
 511145.b3693
COLOMBOS: dgoK


Product      
Name: 2-dehydro-3-deoxygalactonokinase
Synonym(s): DgoK, YidV
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 31.374
Isoelectric point: 5.931
Motif(s):
 
Type Positions Sequence Comment
9 -> 286 DWGSTNLRAWLYQGDHCLESRQSEAGVTRLNGKSPAAVLAEVTTDWREEKTPVVMAGMVGSNVGWKVAPYLSVPACFSSIGEQLTSVGDNIWIIPGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMTGELHHLLLNHSLIGAGLPPQENSADAFTAGLERGLNTPAILPQLFEVRASHVLGTLPREQVSEFLSGLLIGAEVASMRDYVAHQHAITLVAGTSLTARYQQAFQAMGCDVTAVAGDTAFQAGIRSI

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016740 - transferase activity
GO:0016301 - kinase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0008671 - 2-dehydro-3-deoxygalactonokinase activity
biological_process GO:0016310 - phosphorylation
GO:0034194 - D-galactonate catabolic process
GO:0046835 - carbohydrate phosphorylation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P31459
ECOCYC:
 DEHYDDEOXGALACTKIN-MONOMER
ECOLIWIKI:
 b3693
INTERPRO:
 IPR007729
INTERPRO:
 IPR042257
INTERPRO:
 IPR042258
PFAM:
 PF05035
PRIDE:
 P31459
PRODB:
 PRO_000022435
REFSEQ:
 NP_418148
SMR:
 P31459
UNIPROT:
 P31459


Operon      
Name: dgoRKADT         
Operon arrangement:
Transcription unit        Promoter
dgoRKADT


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: DgoR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4257 3875186 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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