RegulonDB RegulonDB 11.1: Gene Form
   

leuX gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

insCD6 intB ahr insD6 insC6 leuX Fis ppGpp terminator anti-terminator anti-anti-terminator TSS_5120 (cluster) TSS_5120 (cluster) TSS_5119 TSS_5119 leuXp leuXp yjgBp8 yjgBp8 yjgBp9 yjgBp9 yjgBp5 yjgBp5 yjgBp10 yjgBp10

Gene      
Name: leuX    Texpresso search in the literature
Synonym(s): ECK4263, EG30053, Su-6, b4270, supP
Genome position(nucleotides): 4496405 --> 4496489
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.12
External database links:  
ASAP:
 ABE-0013986
CGSC:
 561
ECHOBASE:
 EB4216
ECOLIHUB:
 leuX
OU-MICROARRAY:
 b4270
COLOMBOS: leuX


Product      
Name: tRNA-Leu(CAA)
Synonym(s): tRNAleuX
Type: tRNAs
Cellular location: cytosol
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.5 - tRNA
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0030533 - triplet codon-amino acid adaptor activity
Note(s): Note(s): ...[more].
Evidence: [AS-TAS] Traceable author statement
Reference(s): [1] Mohanty BK., et al., 2010
[2] Siekevitz P., et al., 1981
External database links:  
ECOCYC:
 leuX-tRNA
ECOLIWIKI:
 b4270


Operon      
Name: leuX         
Operon arrangement:
Transcription unit        Promoter
leuX


Transcriptional Regulation      
Display Regulation             
Activated by: Fis


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yjgBp10 4496234 reverse nd [COMP-AINF] [3]
  promoter yjgBp5 4496266 reverse nd [COMP-AINF] [3]
  promoter yjgBp9 4496347 reverse nd [COMP-AINF] [3]
  promoter yjgBp8 4496349 reverse nd [COMP-AINF] [3]
  promoter TSS_5119 4497680 forward nd [RS-EPT-CBR] [4]
  promoter TSS_5120 (cluster) 4498243 forward nd [RS-EPT-CBR] [4]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Mohanty BK., Kushner SR., 2010, Processing of the Escherichia coli leuX tRNA transcript, encoding tRNA(Leu5), requires either the 3'-->5' exoribonuclease polynucleotide phosphorylase or RNase P to remove the Rho-independent transcription terminator., Nucleic Acids Res 38(2):597-607

 [2] Siekevitz P., Zamecnik PC., 1981, Ribosomes and protein synthesis., J Cell Biol 91(3 Pt 2):53s-65s

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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