RegulonDB RegulonDB 10.8: Gene Form
   

sraG gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pnp rpsO sraG Cis-reg; leader anti-anti-terminator anti-terminator terminator pnpp pnpp TSS_3451 TSS_3451 sraGp sraGp TSS_3450 TSS_3450 TSS_3449 TSS_3449 TSS_3448 TSS_3448 TSS_3447 (cluster) TSS_3447 (cluster) TSS_3446 (cluster) TSS_3446 (cluster) TSS_3445 TSS_3445 TSS_3444 TSS_3444 TSS_3443 TSS_3443 TSS_3442 TSS_3442 TSS_3441 TSS_3441 TSS_3440 TSS_3440 TSS_3439 TSS_3439 nlpIp2 nlpIp2

Gene      
Name: sraG    Texpresso search in the literature
Synonym(s): ECK3153, G0-8870, b4449, p3, psrA15, psrO
Genome position(nucleotides): 3311183 --> 3311398 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.61
Reference(s): [1] Argaman L., et al., 2001
External database links:  
ASAP:
ABE-0047269
ECHOBASE:
EB4536
PortEco:
psrO
COLOMBOS: sraG


Product      
Name: PsrO
Synonym(s): P3, PsrA15, SraG, p3, psrA15, small regulatory RNA SraG, sraG
Type: small RNA
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related
Gene Ontology Terms (GO)  
molecular_function GO:0003729 - mRNA binding
GO:0048027 - mRNA 5'-UTR binding
biological_process GO:0098787 - mRNA cleavage involved in mRNA processing
GO:0070928 - regulation of mRNA stability, ncRNA-mediated
Note(s): Note(s): ...[more].
Evidence: [IDA] Inferred from direct assay
[IMP] Inferred from mutant phenotype
Reference(s): [1] Argaman L., et al., 2001
[2] Fontaine F., et al., 2016
External database links:  
ECOCYC:
SRAG-RNA
ECOLIWIKI:
b4449


Operon      
Name: sraG         
Operon arrangement:
Transcription unit        Promoter
sraG


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter nlpIp2 3309040 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_3439 3309284 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3440 3309502 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3441 3309519 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3442 3309525 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3443 3309527 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3444 3309617 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3445 3310026 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3446 (cluster) 3310204 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [4]
  promoter TSS_3447 (cluster) 3310283 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [4]
  promoter TSS_3448 3310380 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3449 3310391 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3450 3310952 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_3451 3311249 reverse nd [RS-EPT-CBR] [4]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Argaman L., Hershberg R., Vogel J., Bejerano G., Wagner EG., Margalit H., Altuvia S., 2001, Novel small RNA-encoding genes in the intergenic regions of Escherichia coli., Curr Biol 11(12):941-50

 [2] Fontaine F., Gasiorowski E., Gracia C., Ballouche M., Caillet J., Marchais A., Hajnsdorf E., 2016, The small RNA SraG participates in PNPase homeostasis., RNA 22(10):1560-73

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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