RegulonDB RegulonDB 11.1: Gene Form
   

sroA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

sgrR thiB sroA thiP SgrR Cra Cis-reg; riboswitch terminator sroAp sroAp

Gene      
Name: sroA    Texpresso search in the literature
Synonym(s): ECK4619, G0-9381, b4762, tpe79
Genome position(nucleotides): 75516 <-- 75608
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 59.14
Reference(s): [1] Rodionov DA., et al., 2002
External database links:  
ECOLIHUB:
 sroA
COLOMBOS: sroA


Product      
Name: small RNA SroA
Synonym(s): SroA
Type: small RNA
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related
Gene Ontology Terms (GO)  
Note(s): Note(s): ...[more].
Reference(s): [2] Bastet L., et al., 2017
[3] Chauvier A., et al., 2017
External database links:  
ECOCYC:
 RNA0-404


Operon      
Name: sgrR-sroA-thiBPQ         
Operon arrangement:
Transcription unit        Promoter
sroA
sgrR-sroA-thiBPQ


Transcriptional Regulation      
Display Regulation             
Repressed by: SgrR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Rodionov DA., Vitreschak AG., Mironov AA., Gelfand MS., 2002, Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms., J Biol Chem 277(50):48949-59

 [2] Bastet L., Chauvier A., Singh N., Lussier A., Lamontagne AM., Prevost K., Masse E., Wade JT., Lafontaine DA., 2017, Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation., Nucleic Acids Res 45(12):7474-7486

 [3] Chauvier A., Picard-Jean F., Berger-Dancause JC., Bastet L., Naghdi MR., Dube A., Turcotte P., Perreault J., Lafontaine DA., 2017, Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation., Nat Commun 8:13892

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