RegulonDB RegulonDB 10.8: Gene Form
   

afuB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

afuC insAB2 insB2 afuB insA2 TSS_467 (cluster) TSS_467 (cluster)

Gene      
Name: afuB    Texpresso search in the literature
Synonym(s): ECK0265, G6137, b0263, fbpB
Type: Pseudo Gene
Genome position(nucleotides): 278814 <-- 279162 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.45
Note(s): AfuB is a pseudogene candidate in E. coli K-12. The orthologous gene from E. coli O157:H7 encodes a protein of 692 amino acid residues; afuB from strain K-12 contains an N-terminal deletion compared to the O157 encoded ortholog Homma K,2002. afuBC is a remnant operon; a complete afuABC gene cluster is present in a wide range of bacteria and encodes a binding-protein dependent transport system initially implicated in Fe3+ uptake (afu: Actinobacillus ferric uptake) 8807793, but now believed to transport sugar phosphates 26295949. E. coli K-12 does not contain an afuA ortholog.
Comment from ASAP: The coordinates of afuB have been changed from those reported in the GenBank entry (GBAN:U00096.2) to correspond to the region of similarity to Escherichia coli EDL933 (ASAP:ABH-0024350), removing 14 nucleotides from the N-terminus.
External database links:  
ASAP:
ABE-0000900
ECHOBASE:
EB4025
ECOLIWIKI:
b0263
ECOO157CYC:
AFUB
OU-MICROARRAY:
b0263
PortEco:
afuB
STRING:
316407.85674407
UNIPROT:
P75681
COLOMBOS: afuB


Product      
Name: CP4-6 prophage; ABC transporter membrane protein AfuB
Sequence: Get amino acid sequence Fasta Format
Isoelectric point: 10.482
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
External database links:  
ECOCYC:
G6137-MONOMER
UNIPROT:
P75681


Operon      
Name: insAB2A2B2-afuBC         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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