RegulonDB

Gene
Name:	ykgM
Synonym(s):	ECK0296, G6167, b0296
Genome position(nucleotides):	312514 <-- 312777
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	45.83
External database links:

ASAP:	ABE-0001021
ECHOBASE:	EB4072
ECOLIHUB:	ykgM
OU-MICROARRAY:	b0296
STRING:	511145.b0296
COLOMBOS:	ykgM

Product

Name:

50S ribosomal subunit protein L31B

Synonym(s):

YkgM

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol,ribosome

Molecular weight:

9.92

Isoelectric point:

9.736

Motif(s):

Type	Positions	Sequence	Comment
	1 -> 78	MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFG

Classification:

Multifun Terms (GenProtEC)
		2 - information transfer --> 2.3 - protein related --> 2.3.8 - ribosomal proteins
		5 - cell processes --> 5.5 - adaptations
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005840 - ribosome GO:0022625 - cytosolic large ribosomal subunit
	molecular_function	GO:0003735 - structural constituent of ribosome
	biological_process	GO:0006412 - translation GO:0034224 - cellular response to zinc ion starvation GO:0002181 - cytoplasmic translation

Note(s):

Note(s): ...[more].

Evidence:

[COMP-HINF-FN-FROM-SEQ] Human inference of function from sequence
[EXP-IDA] Inferred from direct assay
[EXP-IMP] Inferred from mutant phenotype

Reference(s):

[1] Graham AI., et al., 2009
[2] Graham AI., et al., 2012
[3] Lilleorg S., et al., 2019
[4] Makarova KS., et al., 2001

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PANTHER:

PDB:

PFAM:

PRIDE:

PRINTS:

PRODB:

PROSITE:

REFSEQ:

SMR:

SWISSMODEL:

UNIPROT:

Operon

Name:

ykgMO

Operon arrangement:

Transcription unit	Promoter
ykgMO	ykgMp

Transcriptional Regulation
	Display Regulation
Repressed by:	Zur

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Graham AI., Hunt S., Stokes SL., Bramall N., Bunch J., Cox AG., McLeod CW., Poole RK., 2009, Severe Zinc Depletion of Escherichia coli: roles for high affinity zinc binding by ZinT, zinc transport and zinc-independent proteins., J Biol Chem 284(27):18377-89
[2] Graham AI., Sanguinetti G., Bramall N., McLeod CW., Poole RK., 2012, Dynamics of a starvation-to-surfeit shift: a transcriptomic and modelling analysis of the bacterial response to zinc reveals transient behaviour of the Fur and SoxS regulators., Microbiology 158(Pt 1):284-92
[3] Lilleorg S., Reier K., Pulk A., Liiv A., Tammsalu T., Peil L., Cate JHD., Remme J., 2019, Bacterial ribosome heterogeneity: Changes in ribosomal protein composition during transition into stationary growth phase., Biochimie 156:169-180
[4] Makarova KS., Ponomarev VA., Koonin EV., 2001, Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins., Genome Biol 2(9):RESEARCH 0033