RegulonDB RegulonDB 11.1: Gene Form
   

proY gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

malZ proY brnQ MalT MalT MalT terminator anti-terminator anti-anti-terminator malZp malZp TSS_507 TSS_507

Gene      
Name: proY    Texpresso search in the literature
Synonym(s): ECK0396, G6233, b0402, yajM
Genome position(nucleotides): 420986 --> 422359
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.91
External database links:  
ASAP:
 ABE-0001398
ECHOBASE:
 EB3376
ECOLIHUB:
 proY
OU-MICROARRAY:
 b0402
STRING:
 511145.b0402
COLOMBOS: proY


Product      
Name: putative transporter ProY
Synonym(s): ProY, ProY cryptic proline APC transporter, YajM
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 50.216
Isoelectric point: 9.999
Motif(s):
 
Type Positions Sequence Comment
15 -> 451 HIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHDR
18 -> 38 FMALGSAIGTGLFYGSADAIK UniProt: Helical.
39 -> 59 MAGPSVLLAYIIGGIAAYIIM UniProt: Helical.
85 -> 105 PLAGYITGWTYCFEILIVAIA UniProt: Helical.
114 -> 134 MGVWFPTVPHWIWVLSVVLII UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015171 - amino acid transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0055085 - transmembrane transport
GO:0003333 - amino acid transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0AAE2
DIP:
 DIP-47977N
ECOCYC:
 PROY-MONOMER
ECOLIWIKI:
 b0402
INTERPRO:
 IPR004841
INTERPRO:
 IPR004840
PFAM:
 PF00324
PRIDE:
 P0AAE2
PRODB:
 PRO_000023605
PROSITE:
 PS00218
REFSEQ:
 NP_414936
UNIPROT:
 P0AAE2


Operon      
Name: brnQ-proY         
Operon arrangement:
Transcription unit        Promoter
brnQ-proY


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_507 420215 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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