RegulonDB

Gene
Name:	ybaT
Synonym(s):	ECK0480, G6262, b0486
Genome position(nucleotides):	512576 --> 513868
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.29
External database links:

ASAP:	ABE-0001690
ECHOBASE:	EB3037
ECOLIHUB:	ybaT
OU-MICROARRAY:	b0486
STRING:	511145.b0486
COLOMBOS:	ybaT

Product

Name:

putative transporter YbaT

Synonym(s):

YbaT

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

45.659

Isoelectric point:

9.194

Motif(s):

Type	Positions	Sequence	Comment
	13 -> 396	LGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVILVGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFI
	15 -> 35	LWNVVSIGIGAMVGAGIFALL	UniProt: Helical.
	39 -> 59	ALLMEASTWVAFAFGGIVAMF	UniProt: Helical.
	89 -> 109	VFSLALSLLYLLTLAVSIAMV	UniProt: Helical.
	129 -> 149	HLILLYALGIIAVMTLFNSLS	UniProt: Helical.

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		4 - transport --> 4.9.B - Putative uncharacterized transport protein
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0022857 - transmembrane transporter activity
	biological_process	GO:0009268 - response to pH GO:0006865 - amino acid transport GO:0055085 - transmembrane transport GO:1990169 - stress response to copper ion

Note(s):

Note(s): ...[more].

Reference(s):

[1] Jindal S., et al., 2019
[2] Permina EA., et al., 2006

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

glsA-ybaT

Operon arrangement:

Transcription unit	Promoter
glsA-ybaT	glsAp

Transcriptional Regulation
	Display Regulation
Activated by:	GadX

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_655	513563	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_656	513566	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_657	513642	forward	nd	[RS-EPT-CBR]	[3]
promoter	TSS_658 (cluster)	513647	forward	nd	[RS-EPT-CBR]	[3]
promoter	cueRp6	513974	forward	nd	[COMP-AINF]	[4]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[COMP-AINF] Inferred computationally without human oversight

Reference(s)
[1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195
[2] Permina EA., Kazakov AE., Kalinina OV., Gelfand MS., 2006, Comparative genomics of regulation of heavy metal resistance in Eubacteria., BMC Microbiol 6:49
[3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[4] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78