RegulonDB RegulonDB 10.10: Gene Form
   

gltI gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

insH3 gltI gltJ sroC FlhDC FlhDC GcvB anti-anti-terminator anti-terminator terminator gltIp1 gltIp1 TSS_780 TSS_780 TSS_779 (cluster) TSS_779 (cluster) TSS_778 TSS_778

Gene      
Name: gltI    Texpresso search in the literature
Synonym(s): ECK0648, G6359, b0655, ybeJ, yzzK
Genome position(nucleotides): 686839 <-- 687747 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.73
External database links:  
ASAP:
 ABE-0002241
ECHOBASE:
 EB2562
ECOLIHUB:
 gltI
OU-MICROARRAY:
 b0655
STRING:
 511145.b0655
COLOMBOS: gltI


Product      
Name: glutamate/aspartate ABC transporter periplasmic binding protein
Synonym(s): GltBP, GltI, YbeJ, YzzK
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space
Molecular weight: 33.42
Isoelectric point: 8.975
Motif(s):
 
Type Positions Sequence
1 -> 22 MQLRKPATAILALALSAGLAQA
23 -> 302 DDAAPAAGSTLDKIAKNGVIVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTSGTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPPKNLNMNFELSDEMKALFKEPNDKALN
42 -> 271 IVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTSGTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFK

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.1 - glutamate
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.p - ABC superfamily, periplasmic binding component
Gene Ontology Terms (GO)  
cellular_component GO:0030288 - outer membrane-bounded periplasmic space
GO:0042597 - periplasmic space
molecular_function GO:0016595 - glutamate binding
GO:0070335 - aspartate binding
biological_process GO:0006865 - amino acid transport
GO:0015813 - L-glutamate transmembrane transport
GO:0070778 - L-aspartate transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-11361N
ECOCYC:
 G6359-MONOMER
ECOLIWIKI:
 b0655
INTERPRO:
 IPR001638
MODBASE:
 P37902
PFAM:
 PF00497
PRIDE:
 P37902
PRODB:
 PRO_000022807
REFSEQ:
 NP_415188
SMART:
 SM00062
SMR:
 P37902
UNIPROT:
 P37902


Operon      
Name: gltI-sroC-gltJKL         
Operon arrangement:
Transcription unit        Promoter
gltIJKL-sroC
gltI-sroC-gltJKL


Transcriptional Regulation      
Display Regulation             
Activated by: FlhDC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_778 687847 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_779 (cluster) 687855 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_780 687863 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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