RegulonDB RegulonDB 10.8: Gene Form
   

gltI gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

insH3 gltI gltJ sroC FlhDC FlhDC GcvB anti-anti-terminator anti-terminator terminator gltIp1 gltIp1 TSS_780 TSS_780 TSS_779 (cluster) TSS_779 (cluster) TSS_778 TSS_778

Gene      
Name: gltI    Texpresso search in the literature
Synonym(s): ECK0648, G6359, b0655, ybeJ, yzzK
Genome position(nucleotides): 686839 <-- 687747 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.73
External database links:  
ASAP:
 ABE-0002241
ECHOBASE:
 EB2562
OU-MICROARRAY:
 b0655
PortEco:
 gltI
STRING:
 511145.b0655
COLOMBOS: gltI


Product      
Name: glutamate/aspartate ABC transporter periplasmic binding protein
Synonym(s): GltBP, GltI, YbeJ, YzzK
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space
Molecular weight: 33.42
Isoelectric point: 8.975
Motif(s):
 
Type Positions Sequence
1 -> 22 MQLRKPATAILALALSAGLAQA
23 -> 302 DDAAPAAGSTLDKIAKNGVIVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTSGTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPPKNLNMNFELSDEMKALFKEPNDKALN
42 -> 271 IVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTSGTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFK

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.1 - glutamate
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.p - ABC superfamily, periplasmic binding component
Gene Ontology Terms (GO)  
cellular_component GO:0030288 - outer membrane-bounded periplasmic space
GO:0042597 - periplasmic space
molecular_function GO:0016595 - glutamate binding
GO:0070335 - aspartate binding
biological_process GO:0006865 - amino acid transport
GO:0015813 - L-glutamate transmembrane transport
GO:0070778 - L-aspartate transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-11361N
ECOCYC:
 G6359-MONOMER
ECOLIWIKI:
 b0655
INTERPRO:
 IPR001638
MODBASE:
 P37902
PFAM:
 PF00497
PRIDE:
 P37902
PRODB:
 PRO_000022807
PROSITE:
 PS01039
REFSEQ:
 NP_415188
SMART:
 SM00062
SMR:
 P37902
UNIPROT:
 P37902


Operon      
Name: gltI-sroC-gltJKL         
Operon arrangement:
Transcription unit        Promoter
gltIJKL-sroC
gltI-sroC-gltJKL


Transcriptional Regulation      
Display Regulation             
Activated by: FlhDC


Regulation by small RNA    
  Display Regulation
small RNA gcvB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_778 687847 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_779 (cluster) 687855 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_780 687863 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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