Gene
Name:	hcp
Synonym(s):	ECK0864, G6457, b0873, priS, ybjW
Genome position(nucleotides):	912162 <-- 913814
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	54.75
External database links:

ASAP:	ABE-0002962
ECHOBASE:	EB3456
ECOLIHUB:	hcp
OU-MICROARRAY:	b0873
STRING:	511145.b0873
COLOMBOS:	hcp

Transcriptional Regulation
	Display Regulation
Activated by:	FNR, OxyR, NarL, NarP
Repressed by:	NsrR

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	hcrp3	912200		reverse	nd	[COMP-AINF]	[5]
	promoter	TSS_1024	912408		reverse	nd	[RS-EPT-CBR]	[6]

Evidence
[COMP-AINF] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Chismon DL., Browning DF., Farrant GK., Busby SJ., 2010, Unusual organization, complexity and redundancy at the Escherichia coli hcp-hcr operon promoter., Biochem J 430(1):61-8
[2] Rodionov DA., Dubchak IL., Arkin AP., Alm EJ., Gelfand MS., 2005, Dissimilatory metabolism of nitrogen oxides in bacteria: comparative reconstruction of transcriptional networks., PLoS Comput Biol 1(5):e55
[3] Seth D., Hess DT., Hausladen A., Wang L., Wang YJ., Stamler JS., 2018, A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation., Mol Cell 69(3):451-464.e6
[4] van den Berg WA., Hagen WR., van Dongen WM., 2000, The hybrid-cluster protein ('prismane protein') from Escherichia coli. Characterization of the hybrid-cluster protein, redox properties of the [2Fe-2S] and [4Fe-2S-2O] clusters and identification of an associated NADH oxidoreductase containing FAD and [2Fe-2S]., Eur J Biochem 267(3):666-76
[5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[6] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.