RegulonDB

Gene
Name:	ycaM
Synonym(s):	ECK0890, G6466, b0899
Genome position(nucleotides):	947229 --> 948659 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	47.17
External database links:

ASAP:	ABE-0003058
ECHOBASE:	EB3461
ECOLIHUB:	ycaM
OU-MICROARRAY:	b0899
STRING:	511145.b0899
COLOMBOS:	ycaM

Product

Name:

putative transporter YcaM

Synonym(s):

YcaM

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

52.496

Isoelectric point:

9.502

Motif(s):

Type	Positions	Sequence
	415 -> 435	AMTVGIWCFAFTAFACLTGIF
	126 -> 146	YSVVALQGLTLVLFIFFMWVA
	155 -> 175	IVGSVAGIAMFVMSLLYVAMA
	344 -> 364	GYFLTLVLVAILIMLPTLGIG
	39 -> 59	VVVFSWVFIFALYFTPYALIV

Classification:

Multifun Terms (GenProtEC)
		4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0015171 - amino acid transmembrane transporter activity GO:0022857 - transmembrane transporter activity
	biological_process	GO:0006865 - amino acid transport GO:0055085 - transmembrane transport GO:0003333 - amino acid transmembrane transport

Note(s):

Note(s): ...[more].

Evidence:

[IMP] Inferred from mutant phenotype

Reference(s):

[1] Jindal S., et al., 2019
[2] Serina S., et al., 2004

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

ycaM

Operon arrangement:

Transcription unit	Promoter
ycaM

RNA cis-regulatory element

Attenuation:	Transcriptional

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	ycaMp2	947120	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.514. P-value: 6.067e-5 Read more >	[ICWHO]	[3]
promoter	ycaMp4	947127	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.948. P-value: 1.980e-5 Read more >	[ICWHO]	[3]
promoter	ycaMp5	947144	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 5.25. P-value: 2.902e-6 Read more >	[ICWHO]	[3]
promoter	ycaMp3	947145	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.703. P-value: 9.051e-5 Read more >	[ICWHO]	[3]
promoter	ycaKp3	949547	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.91. P-value: 5.714e-5 Read more >	[ICWHO]	[3]

Evidence
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195
[2] Serina S., Nozza F., Nicastro G., Faggioni F., Mottl H., Deho G., Polissi A., 2004, Scanning the Escherichia coli chromosome by random transposon mutagenesis and multiple phenotypic screening., Res Microbiol 155(8):692-701
[3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78