RegulonDB RegulonDB 11.0: Gene Form
   

yccS gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yccS sxy sulA yccF CRP-Sxy LexA RcdA RcdA yccSp2 yccSp2 yccSp3 yccSp3 TSS_1285 TSS_1285 sxyp sxyp TSS_1283 TSS_1283 sulAp sulAp

Gene      
Name: yccS    Texpresso search in the literature
Synonym(s): ECK0951, G6495, b0960
Genome position(nucleotides): 1021730 <-- 1023883
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.23
External database links:  
ASAP:
 ABE-0003251
ECHOBASE:
 EB3485
ECOLIHUB:
 yccS
OU-MICROARRAY:
 b0960
STRING:
 511145.b0960
COLOMBOS: yccS


Product      
Name: putative transporter YccS
Synonym(s): YccS
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 81.668
Isoelectric point: 7.249
Motif(s):
 
Type Positions Sequence Comment
11 -> 31 WNSAWLYYARIFIALCGTTAF UniProt: Helical.
33 -> 53 WWLGDVKLTIPLTLGMVAAAL UniProt: Helical.
66 -> 345 NLIITLFCFFIASASVELLFPWPWLFAIGLTLSTSGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIGHLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDQSQAPLYDLALANGLLMATLNQTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFRFQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTLGFLLNNLRAIDAQL
67 -> 87 LIITLFCFFIASASVELLFPW UniProt: Helical.
89 -> 109 WLFAIGLTLSTSGFILLGGLG UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P75870
DIP:
 DIP-11498N
ECOCYC:
 G6495-MONOMER
ECOLIWIKI:
 b0960
INTERPRO:
 IPR010020
INTERPRO:
 IPR010019
INTERPRO:
 IPR032692
PFAM:
 PF13515
PFAM:
 PF12805
PRIDE:
 P75870
REFSEQ:
 NP_415480
SMR:
 P75870
UNIPROT:
 P75870


Operon      
Name: yccFS         
Operon arrangement:
Transcription unit        Promoter
yccFS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1283 1020949 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_1285 1021378 forward nd [RS-EPT-CBR] [2]
  promoter yccSp3 1023976 reverse nd [ICWHO] [3]
  promoter yccSp2 1023994 reverse nd [ICWHO] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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