RegulonDB RegulonDB 10.8: Gene Form
   

nagZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

nagZ thiK ycfP lpoB TSS_1439 TSS_1439 TSS_1438 TSS_1438 TSS_1437 TSS_1437 TSS_1436 TSS_1436

Gene      
Name: nagZ    Texpresso search in the literature
Synonym(s): ECK1093, G6567, b1107, ycfO
Genome position(nucleotides): 1164095 --> 1165120 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.02
External database links:  
ASAP:
ABE-0003737
ECHOBASE:
EB3207
OU-MICROARRAY:
b1107
PortEco:
nagZ
STRING:
511145.b1107
COLOMBOS: nagZ


Product      
Name: β-N-acetylhexosaminidase
Synonym(s): NagZ, YcfO, hexosaminidase
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 37.595
Isoelectric point: 6.237
Motif(s):
 
Type Positions Sequence
7 -> 318 DVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNRLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSA
163 -> 164 KH

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.34 - murein turnover, recycling
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0102148 - N-acetyl-beta-D-galactosaminidase activity
GO:0016787 - hydrolase activity
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 - hydrolase activity, acting on glycosyl bonds
GO:0004563 - beta-N-acetylhexosaminidase activity
biological_process GO:0008152 - metabolic process
GO:0051301 - cell division
GO:0005975 - carbohydrate metabolic process
GO:0007049 - cell cycle
GO:0009252 - peptidoglycan biosynthetic process
GO:0009254 - peptidoglycan turnover
GO:0008360 - regulation of cell shape
GO:0071555 - cell wall organization
Note(s): Note(s): ...[more].
External database links:  
CAZY:
GH3
ECOCYC:
G6567-MONOMER
ECOLIWIKI:
b1107
INTERPRO:
IPR019800
INTERPRO:
IPR017853
INTERPRO:
IPR022956
INTERPRO:
IPR036962
INTERPRO:
IPR001764
MODBASE:
P75949
PFAM:
PF00933
PRIDE:
P75949
PRODB:
PRO_000023341
PROSITE:
PS00775
REFSEQ:
NP_415625
SMR:
P75949
SWISSMODEL:
P75949
UNIPROT:
P75949


Operon      
Name: hinT-ycfL-lpoB-thiK-nagZ-ycfP         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1436 1163603 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1437 1164943 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1438 1165016 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1439 1165531 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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