RegulonDB RegulonDB 10.9: Gene Form
   

iraM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mcrA iraM icdC ymgK PhoP ArcA FNR PhoP ArcA iraMp2 iraMp2 iraMp iraMp

Gene      
Name: iraM    Texpresso search in the literature
Synonym(s): ECK1147, G6600, b1160, elb1, elbA, ycgW
Genome position(nucleotides): 1211680 <-- 1212003 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
33.95
External database links:  
ASAP:
ABE-0003893
ECHOBASE:
EB3644
ECOLIHUB:
iraM
OU-MICROARRAY:
b1160
STRING:
511145.b1160
COLOMBOS: iraM


Product      
Name: anti-adaptor protein IraM, inhibitor of σS proteolysis
Synonym(s): ElbA, IraM, YcgW
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 12.133
Isoelectric point: 9.004
Classification:
Multifun Terms (GenProtEC)  
  3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional
  5 - cell processes --> 5.5 - adaptations --> 5.5.3 - starvation
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
molecular_function GO:0005515 - protein binding
GO:0043856 - anti-sigma factor antagonist activity
biological_process GO:0045893 - positive regulation of transcription, DNA-templated
GO:0009267 - cellular response to starvation
GO:0010350 - cellular response to magnesium starvation
GO:0042177 - negative regulation of protein catabolic process
GO:0071468 - cellular response to acidic pH
Note(s): Note(s): ...[more].
Evidence: [IDA] Inferred from direct assay
Reference(s): [1] Bougdour A., et al., 2008
External database links:  
ECOCYC:
G6600-MONOMER
ECOLIWIKI:
b1160
INTERPRO:
IPR014448
PRIDE:
P75987
PRODB:
PRO_000023029
REFSEQ:
NP_415678
UNIPROT:
P75987


Operon      
Name: iraM         
Operon arrangement:
Transcription unit        Promoter
iraM
iraM


Transcriptional Regulation      
Display Regulation             
Activated by: PhoP, FNR, ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Bougdour A., Cunning C., Baptiste PJ., Elliott T., Gottesman S., 2008, Multiple pathways for regulation of sigmaS (RpoS) stability in Escherichia coli via the action of multiple anti-adaptors., Mol Microbiol 68(2):298-313


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