RegulonDB RegulonDB 10.8: Gene Form
   

ycgZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

bluF ymgA ycgZ RcdA BluR RcdA MarA ycgZp ycgZp bluFp7 bluFp7 bluFp bluFp

Gene      
Name: ycgZ    Texpresso search in the literature
Synonym(s): ECK1151, G6604, b1164
Genome position(nucleotides): 1215789 --> 1216025 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
41.77
External database links:  
ASAP:
ABE-0003907
ECHOBASE:
EB4036
OU-MICROARRAY:
b1164
PortEco:
ycgZ
STRING:
511145.b1164
COLOMBOS: ycgZ


Product      
Name: putative two-component system connector protein YcgZ
Synonym(s): YcgZ
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 8.769
Isoelectric point: 6.942
Motif(s):
 
Type Positions Sequence
27 -> 63 QETLGEIVTEILKDGRNLSRKSLCAKLLCRLEHATGE

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
molecular_function GO:0005515 - protein binding
biological_process GO:0045892 - negative regulation of transcription, DNA-templated
GO:0071468 - cellular response to acidic pH
Note(s): Note(s): ...[more].
Evidence: [IMP] Inferred from mutant phenotype
Reference(s): [1] Duval V., et al., 2017
[2] Ryo M., et al., 2013
[3] Tschowri N., et al., 2012
External database links:  
ECOCYC:
G6604-MONOMER
ECOLIWIKI:
b1164
INTERPRO:
IPR024753
PFAM:
PF10798
PRIDE:
P75991
REFSEQ:
NP_415682
UNIPROT:
P75991


Operon      
Name: ycgZ-ymgA-ariR-ymgC         
Operon arrangement:
Transcription unit        Promoter
ycgZ-ymgA-ariR-ymgC
ariR
 


Transcriptional Regulation      
Display Regulation             
Activated by: MarA
Repressed by: BluR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter bluFp7 1215613 reverse Similarity to the consensus
Read more >
[ICWHO] [4]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Duval V., Foster K., Brewster J., Levy SB., 2017, A Novel Regulatory Cascade Involving BluR, YcgZ, and Lon Controls the Expression of Escherichia coli OmpF Porin., Front Microbiol 8:1148

 [2] Ryo M., Oshikoshi Y., Doi S., Motoki S., Niimi A., Aoki S., 2013, Firefly luciferase as the reporter for transcriptional response to the environment in Escherichia coli., Anal Biochem 443(2):211-3

 [3] Tschowri N., Lindenberg S., Hengge R., 2012, Molecular function and potential evolution of the biofilm-modulating blue light-signalling pathway of Escherichia coli., Mol Microbiol 85(5):893-906

 [4] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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