RegulonDB

RegulonDB RegulonDB 10.9: Gene Form

pdeG gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	pdeG
Synonym(s):	ECK1155, G6608, b1168, ycgG
Genome position(nucleotides):	1217328 --> 1218851 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	44.62
External database links:

ASAP:	ABE-0003918
ECHOBASE:	EB3647
ECOLIHUB:	ycgG
ECOO157CYC:	Z1528
ECOO157CYC:	Z2221
OU-MICROARRAY:	b1168
STRING:	511145.b1168
COLOMBOS:	pdeG

Product

Name:

putative c-di-GMP phosphodiesterase PdeG

Synonym(s):

PdeG, YcgG

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

periplasmic space,inner membrane,cytosol

Molecular weight:

56.906

Isoelectric point:

6.985

Motif(s):

Type	Positions	Sequence
	5 -> 26	LIPILVAICLFITGVAILNIQL
	223 -> 239	GILIFILLIACAAAFLL
	217 -> 237	LIDKGFGILIFILLIACAAAF
	32 -> 217	AEYLAGARYAANNINHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLPGNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNVPLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRL
	4 -> 24	TLIPILVAICLFITGVAILNI

Classification:

Multifun Terms (GenProtEC)
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0030288 - outer membrane-bounded periplasmic space GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0016787 - hydrolase activity GO:0071111 - cyclic-guanylate-specific phosphodiesterase activity

Note(s):

Note(s): ...[more].

Reference(s):

[1] Sarenko O., et al., 2017

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

ECOO157CYC:

ECOO157CYC:

INTERPRO:

INTERPRO:

INTERPRO:

PFAM:

PFAM:

PRIDE:

PROSITE:

REFSEQ:

SMART:

SMR:

UNIPROT:

Operon

Name:

pdeG

Operon arrangement:

Transcription unit	Promoter
pdeG

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	ycgGp7	1217307		forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 7.693. P-value: 3.581e-6 Read more >	[ICWHO]	[2]
	promoter	ymgFp1	1218814		forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: 1.0. P-value: 5.197e-7 Read more >	[ICWHO]	[2]
	promoter	ymgFp7	1218937		forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.39. P-value: 9.516e-5 Read more >	[ICWHO]	[2]
	promoter	ymgFp11	1218940		forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.788. P-value: 2.646e-5 Read more >	[ICWHO]	[2]
	promoter	ymgFp10	1218953		forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.294. P-value: 1.033e-5 Read more >	[ICWHO]	[2]

Evidence
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Sarenko O., Klauck G., Wilke FM., Pfiffer V., Richter AM., Herbst S., Kaever V., Hengge R., 2017, More than Enzymes That Make or Break Cyclic Di-GMP-Local Signaling in the Interactome of GGDEF/EAL Domain Proteins of Escherichia coli., MBio 8(5)
[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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