RegulonDB RegulonDB 11.1: Gene Form
   

ynfM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ynfM ynfL asr unknown PhoB RcdA RstA RcdA terminator asrp2 asrp2 asrp asrp ynfMp ynfMp ynfLp6 ynfLp6 ynfMp5 ynfMp5 ynfMp4 ynfMp4

Gene      
Name: ynfM    Texpresso search in the literature
Synonym(s): ECK1591, G6854, b1596, yzyC
Genome position(nucleotides): 1669699 --> 1670952
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.95
External database links:  
ASAP:
 ABE-0005333
ECHOBASE:
 EB2785
ECOLIHUB:
 ynfM
OU-MICROARRAY:
 b1596
STRING:
 511145.b1596
COLOMBOS: ynfM


Product      
Name: putative transporter YnfM
Synonym(s): YnfM, YzyC
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 45.257
Isoelectric point: 10.847
Motif(s):
 
Type Positions Sequence Comment
1 -> 22 MSRTTTVDGAPASDTDKQSISQ UniProt: Disordered; Sequence Annotation Type: region of interest.
39 -> 59 LALFSAGLATFALLYCVQPIL UniProt: Helical.
41 -> 260 LFSAGLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKPVMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAFSMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFRPTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNY
74 -> 94 SISLSISTAMLAIGLLFTGPL UniProt: Helical.
102 -> 122 PVMVTALLLASICTLLSTMMT UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P43531
ECOCYC:
 B1596-MONOMER
ECOLIWIKI:
 b1596
INTERPRO:
 IPR020846
INTERPRO:
 IPR011701
INTERPRO:
 IPR005829
INTERPRO:
 IPR036259
MODBASE:
 P43531
PFAM:
 PF07690
PRIDE:
 P43531
PROSITE:
 PS50850
PROSITE:
 PS00216
REFSEQ:
 NP_416113
UNIPROT:
 P43531


Operon      
Name: ynfM         
Operon arrangement:
Transcription unit        Promoter
ynfM


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ynfMp4 1669630 forward nd [COMP-AINF] [2]
  promoter ynfMp5 1669633 forward nd [COMP-AINF] [2]
  promoter ynfLp6 1669652 reverse nd [COMP-AINF] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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