RegulonDB

Gene
Name:	asr
Synonym(s):	ECK1592, G6855, b1597
Genome position(nucleotides):	1671376 --> 1671684
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	51.13
External database links:

ASAP:	ABE-0005337
ECHOBASE:	EB2069
ECOLIHUB:	asr
OU-MICROARRAY:	b1597
STRING:	511145.b1597
COLOMBOS:	asr

Product

Name:

acid shock protein

Synonym(s):

Asr

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

periplasmic space

Molecular weight:

10.591

Isoelectric point:

11.374

Motif(s):

Type	Positions	Sequence	Comment
	1 -> 21	MKKVLALVVAAAMGLSSAAFA
	21 -> 39	AAETTTTPAPTATTTKAAP	UniProt: Polar residues; Sequence Annotation Type: compositionally biased region.
	22 -> 58	AETTTTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQ
	40 -> 67	AKTTHHKKQHKAAPAQKAQAAKKHHKNT	UniProt: Basic residues; Sequence Annotation Type: compositionally biased region.
	59 -> 102	AAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		5 - cell processes --> 5.5 - adaptations --> 5.5.4 - pH
Gene Ontology Terms (GO)
	cellular_component	GO:0030288 - outer membrane-bounded periplasmic space GO:0042597 - periplasmic space
	biological_process	GO:0006950 - response to stress GO:0010447 - response to acidic pH GO:0010043 - response to zinc ion

Note(s):

Note(s): ...[more].

Evidence:

[EXP-IMP] Inferred from mutant phenotype

Reference(s):

[1] Ramos-Morales F. 2012
[2] Seputiene V., et al., 2003

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PRIDE:

PRODB:

REFSEQ:

UNIPROT:

Operon

Name:

asr

Operon arrangement:

Transcription unit	Promoter
asr	asrp
asr	asrp2

Transcriptional Regulation
	Display Regulation
Activated by:	PhoB, RcdA, RstA
Repressed by:	H-NS

RNA cis-regulatory element

Attenuation:	Translational

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Ramos-Morales F., 2012, Acidic pH: enemy or ally for enteric bacteria?, Virulence 3(2):103-6
[2] Seputiene V., Motiej??nas D., Suziedelis K., Tomenius H., Normark S., Melefors O., Suziedeliene E., 2003, Molecular characterization of the acid-inducible asr gene of Escherichia coli and its role in acid stress response., J Bacteriol 185(8):2475-84