RegulonDB RegulonDB 11.1: Gene Form
   

ydiM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ydiN ydiM ydiL ydiNp6 ydiNp6 ydiMp1 ydiMp1 ydiMp5 ydiMp5

Gene      
Name: ydiM    Texpresso search in the literature
Synonym(s): ECK1688, G6916, b1690
Genome position(nucleotides): 1771071 --> 1772285
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 44.94
External database links:  
ASAP:
 ABE-0005645
ECHOBASE:
 EB3729
ECOLIHUB:
 ydiM
OU-MICROARRAY:
 b1690
STRING:
 511145.b1690
COLOMBOS: ydiM


Product      
Name: putative exporter YdiM
Synonym(s): YdiM
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 44.608
Isoelectric point: 9.882
Motif(s):
 
Type Positions Sequence Comment
6 -> 26 FPTALGLYFNYLVHGMGVLLM UniProt: Helical.
14 -> 291 FNYLVHGMGVLLMSLNMASLETLWQTNAAGVSIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILQTNNIIIAYVFGFLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWFGWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGYISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTTLLMLYTFISFIALFT
44 -> 64 VSIVISSLGIGRLSVLLFAGL UniProt: Helical.
85 -> 105 FFFGILQTNNIIIAYVFGFLA UniProt: Helical.
133 -> 153 ILIKAFVSSGQFLLPLIISLL UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
[2] Nishino K., et al., 2001
[3] Wang C., et al., 2015
External database links:  
ALPHAFOLD:
 P76197
DIP:
 DIP-11754N
ECOCYC:
 B1690-MONOMER
ECOLIWIKI:
 b1690
INTERPRO:
 IPR020846
INTERPRO:
 IPR011701
INTERPRO:
 IPR036259
INTERPRO:
 IPR005829
MODBASE:
 P76197
PFAM:
 PF07690
PRIDE:
 P76197
PROSITE:
 PS00216
PROSITE:
 PS50850
REFSEQ:
 NP_416205
UNIPROT:
 P76197


Operon      
Name: ydiM         
Operon arrangement:
Transcription unit        Promoter
ydiM


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ydiMp5 1770926 forward nd [COMP-AINF] [4]
  promoter ydiMp1 1770930 forward nd [COMP-AINF] [4]
  promoter ydiNp6 1772409 forward nd [COMP-AINF] [4]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Nishino K., Yamaguchi A., 2001, Analysis of a complete library of putative drug transporter genes in Escherichia coli., J Bacteriol 183(20):5803-12

 [3] Wang C., Yang L., Shah AA., Choi ES., Kim SW., 2015, Dynamic interplay of multidrug transporters with TolC for isoprenol tolerance in Escherichia coli., Sci Rep 5:16505

 [4] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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