RegulonDB RegulonDB 10.10: Gene Form
   

yebQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yebQ htpX kdgR TSS_2175 TSS_2175 kdgRp1 kdgRp1 yebQp5 yebQp5 yebQp4 yebQp4 kdgRp9 kdgRp9 kdgRp8 kdgRp8

Gene      
Name: yebQ    Texpresso search in the literature
Synonym(s): ECK1827, G7004, b1828
Genome position(nucleotides): 1910276 --> 1911649 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.33
External database links:  
ASAP:
 ABE-0006085
ECHOBASE:
 EB3773
ECOLIHUB:
 yebQ
OU-MICROARRAY:
 b1828
STRING:
 511145.b1828
COLOMBOS: yebQ


Product      
Name: putative transporter YebQ
Synonym(s): YebQ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 48.152
Isoelectric point: 9.926
Motif(s):
 
Type Positions Sequence
269 -> 289 LFSLSICTSVCSFCAQMLAMV
144 -> 164 INSFIVAVSSAAGPTIAAAIL
22 -> 412 VIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSG
166 -> 186 IASWKWLFLINVPLGIIALLL
357 -> 377 SPADINIIWPMILCGAGFGLF

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ECOCYC:
 B1828-MONOMER
ECOLIWIKI:
 b1828
INTERPRO:
 IPR020846
INTERPRO:
 IPR036259
INTERPRO:
 IPR011701
INTERPRO:
 IPR001411
MODBASE:
 P76269
PANTHER:
 PTHR23501
PFAM:
 PF07690
PRIDE:
 P76269
PROSITE:
 PS50850
REFSEQ:
 NP_416342
UNIPROT:
 P76269


Operon      
Name: yebQ         
Operon arrangement:
Transcription unit        Promoter
yebQ


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter kdgRp8 1910125 reverse nd [ICWHO] [2]
  promoter kdgRp9 1910140 reverse nd [ICWHO] [2]
  promoter yebQp4 1910157 forward nd [ICWHO] [2]
  promoter yebQp5 1910159 forward nd [ICWHO] [2]
  promoter kdgRp1 1910253 reverse nd [ICWHO] [2]
  promoter TSS_2175 1912259 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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