RegulonDB RegulonDB 10.10: Gene Form
   

msrQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

msrP zinT msrQ OxyR Zur zinTp zinTp TSS_2282 TSS_2282 TSS_2281 TSS_2281

Gene      
Name: msrQ    Texpresso search in the literature
Synonym(s): ECK1968, G7060, b1972, yedZ
Genome position(nucleotides): 2040483 --> 2041118 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 47.96
External database links:  
ASAP:
 ABE-0006542
ECHOBASE:
 EB3801
ECOLIHUB:
 yedZ
OU-MICROARRAY:
 b1972
STRING:
 511145.b1972
COLOMBOS: msrQ


Product      
Name: protein-L-methionine sulfoxide reductase heme-binding subunit MsrQ
Synonym(s): MsrQ, YedZ, periplasmic protein-L-methionine sulfoxide reductase heme binding subunit
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 24.068
Isoelectric point: 11.403
Motif(s):
 
Type Positions Sequence
10 -> 30 WLKVCLHLAGLLPFLWLVWAI
45 -> 67 HFTGRTALKFLLATLLITPLARY
171 -> 189 IISPQPLIYAGLAVLLLAL
116 -> 136 PYLTLGIISWVILLALAFTST
150 -> 167 LHNFVYLVAILAPIHYLW

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.5 - adaptations --> 5.5.6 - other (mechanical, nutritional, oxidative stress)
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0009055 - electron transfer activity
GO:0046872 - metal ion binding
GO:0010181 - FMN binding
GO:0016679 - oxidoreductase activity, acting on diphenols and related substances as donors
GO:0020037 - heme binding
biological_process GO:0030091 - protein repair
GO:0022900 - electron transport chain
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 G7060-MONOMER
ECOLIWIKI:
 b1972
INTERPRO:
 IPR022837
INTERPRO:
 IPR013130
PANTHER:
 PTHR36964
PFAM:
 PF01794
PRIDE:
 P76343
REFSEQ:
 NP_416481
UNIPROT:
 P76343


Operon      
Name: msrPQ         
Operon arrangement:
Transcription unit        Promoter
msrPQ


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2281 2039749 forward nd [RS-EPT-CBR] [1]
  promoter TSS_2282 2041344 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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