RegulonDB RegulonDB 11.1: Gene Form
   

yeeO gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yeeO asnW asnU terminator yeeOp6 yeeOp6 TSS_2299 TSS_2299 asnUp asnUp TSS_2298 TSS_2298 yeeOp1 yeeOp1 yeeOp7 yeeOp7 TSS_2297 TSS_2297 TSS_2296 TSS_2296

Gene      
Name: yeeO    Texpresso search in the literature
Synonym(s): ECK1980, G7070, b1985
Genome position(nucleotides): 2058203 <-- 2059846
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.3
External database links:  
ASAP:
 ABE-0006586
ECHOBASE:
 EB3164
ECOLIHUB:
 yeeO
OU-MICROARRAY:
 b1985
STRING:
 511145.b1985
COLOMBOS: yeeO


Product      
Name: FMN/FAD exporter
Synonym(s): YeeO
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 60.061
Isoelectric point: 10.379
Motif(s):
 
Type Positions Sequence Comment
94 -> 114 ITPLAVPIFMENACVLLMGVL UniProt: Helical.
100 -> 260 PIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIIS
139 -> 159 VIMAFFAAIDLGTTVVVAFSL UniProt: Helical.
174 -> 194 SLVIMTLFAVLLATLIHHFGE UniProt: Helical.
211 -> 231 LALTYLELTVLSYPAAAITLI UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015297 - antiporter activity
GO:0042910 - xenobiotic transmembrane transporter activity
GO:0071916 - dipeptide transmembrane transporter activity
GO:0015230 - FAD transmembrane transporter activity
GO:0044610 - FMN transmembrane transporter activity
biological_process GO:0015031 - protein transport
GO:0015833 - peptide transport
GO:0055085 - transmembrane transport
GO:0042908 - xenobiotic transport
GO:1901264 - carbohydrate derivative transport
GO:0035442 - dipeptide transmembrane transport
GO:0035350 - FAD transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] McAnulty MJ., et al., 2014
External database links:  
ALPHAFOLD:
 P76352
ECOCYC:
 YEEO-MONOMER
ECOLIWIKI:
 b1985
INTERPRO:
 IPR002528
PFAM:
 PF01554
PRIDE:
 P76352
REFSEQ:
 NP_416491
UNIPROT:
 P76352


Operon      
Name: yeeO         
Operon arrangement:
Transcription unit        Promoter
yeeO


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2296 2059688 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2297 2059690 reverse nd [RS-EPT-CBR] [2]
  promoter yeeOp7 2059722 reverse nd [COMP-AINF] [3]
  promoter yeeOp1 2059828 reverse nd [COMP-AINF] [3]
  promoter TSS_2298 2059842 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2299 2059851 forward nd [RS-EPT-CBR] [2]
  promoter yeeOp6 2059875 reverse nd [COMP-AINF] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] McAnulty MJ., Wood TK., 2014, YeeO from Escherichia coli exports flavins., Bioengineered 5(6):386-92

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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