RegulonDB

Gene
Name:	wza
Synonym(s):	ECK2056, G7107, b2062
Genome position(nucleotides):	2136104 <-- 2137243 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.77
External database links:

ASAP:	ABE-0006825
ECHOBASE:	EB3336
ECOLIHUB:	wza
OU-MICROARRAY:	b2062
STRING:	511145.b2062
COLOMBOS:	wza

Product

Name:

outer membrane polysaccharide export protein Wza

Synonym(s):

Wza

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

outer membrane

Molecular weight:

41.91

Isoelectric point:

6.532

Motif(s):

Type	Positions	Sequence
	21 -> 379	CTVLPGSNMSTMGKDVIKQQDADFDLDKMVNVYPLTPRLIDQLRPRPNVARPNMTLESEIANYQYRVGPGDVLNVTVWDHPELTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVHVVGKTLAEIRSDITGRLATYIADPQVDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHNGREERISLQALMQNGDLNQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGMTLTEALGNAEGIDMTTSNASGIFVIRPLKGEGGRNGKIANIYQLDMSDATSLVMATEFRLQPYDVVYVTTAPVSRWNRLINQLLPTISGVRYMTDTASDIHNW
	321 -> 321	D
	1 -> 20	MMKSKMKLMPLLVSVTLISG
	82 -> 165	NYQYRVGPGDVLNVTVWDHPELTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVHVVGKTLAEIRSDITGRLATYIADPQVDVNI
	173 -> 221	AYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHNGRE

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.2 - colanic acid (M antigen)
		4 - transport --> 4.9.B - Putative uncharacterized transport protein
Gene Ontology Terms (GO)
	cellular_component	GO:0009279 - cell outer membrane GO:0016020 - membrane GO:0016021 - integral component of membrane GO:0046930 - pore complex
	molecular_function	GO:0005515 - protein binding GO:0015288 - porin activity GO:0015159 - polysaccharide transmembrane transporter activity
	biological_process	GO:0000271 - polysaccharide biosynthetic process GO:0006811 - ion transport GO:0008643 - carbohydrate transport GO:0046377 - colanic acid metabolic process GO:0015774 - polysaccharide transport GO:0055085 - transmembrane transport

Note(s):

Note(s): ...[more].

Reference(s):

[1] Ford RC., et al., 2009
[2] Rao S., et al., 2020

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

PFAM:

PFAM:

PFAM:

PRIDE:

PROSITE:

REFSEQ:

SMR:

UNIPROT:

Transcriptional Regulation
	Display Regulation
Activated by:	RcsAB

Reference(s)
[1] Ford RC., Brunkan-LaMontagne AL., Collins RF., Clarke BR., Harris R., Naismith JH., Whitfield C., 2009, Structure-function relationships of the outer membrane translocon Wza investigated by cryo-electron microscopy and mutagenesis., J Struct Biol 166(2):172-82
[2] Rao S., Bates GT., Matthews CR., Newport TD., Vickery ON., Stansfeld PJ., 2020, Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations., Structure 28(4):475-487.e3

RNA cis-regulatory element

Cis-reg	JUMPstart RNA