RegulonDB RegulonDB 10.9: Gene Form
   

elaD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yfbK elaD rbn TSS_2529 TSS_2529 elaDp8 elaDp8 elaAp4 elaAp4 elaAp3 elaAp3

Gene      
Name: elaD    Texpresso search in the literature
Synonym(s): ECK2263, G7176, b2269
Genome position(nucleotides): 2382713 --> 2383924 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
35.4
External database links:  
ASAP:
ABE-0007499
ECHOBASE:
EB4009
ECOLIHUB:
elaD
OU-MICROARRAY:
b2269
STRING:
511145.b2269
COLOMBOS: elaD


Product      
Name: protease ElaD
Synonym(s): ElaD, deubiquitinase
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 46.078
Isoelectric point: 6.795
Motif(s):
 
Type Positions Sequence
165 -> 362 QLTTDEIACYLQKIAANAKNTQVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPNEVQLFPINTGGHWILVSLQKIVNKKNNKLQIKCVIFNSLRALGYDKENSLKRVINSFNSELMGEMSNNNIKVHLNEPEIIFLHADLQQYLSQSCGAFVCMAAQEVIEQRESNSDSAPYTLLKNHADRFKKYSAEEQYEIDFQH
16 -> 16 Q
313 -> 313 C

 

Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.3 - protein related --> 2.3.6 - turnover, degradation
Gene Ontology Terms (GO)  
molecular_function GO:0008233 - peptidase activity
GO:0016787 - hydrolase activity
GO:0008234 - cysteine-type peptidase activity
biological_process GO:0006508 - proteolysis
GO:0016579 - protein deubiquitination
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
G7176-MONOMER
ECOLIWIKI:
b2269
INTERPRO:
IPR038765
INTERPRO:
IPR003653
PFAM:
PF02902
PRIDE:
Q47013
PRODB:
PRO_000022507
REFSEQ:
NP_416772
UNIPROT:
Q47013


Operon      
Name: elaD         
Operon arrangement:
Transcription unit        Promoter
elaD


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter elaAp3 2381614 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter elaAp4 2381686 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter elaDp8 2382654 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_2529 2385404 forward nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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