RegulonDB RegulonDB 11.1: Gene Form
   

yfeZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

amiA yfeY yfeZ ypeA IHF IHF anti-anti-terminator hemFp1 hemFp1 hemFp2 hemFp2 hemFp3 hemFp3 TSS_2747 (cluster) TSS_2747 (cluster) amiAp amiAp yfeZp3 yfeZp3 yfeYp yfeYp yfeXp5 yfeXp5

Gene      
Name: yfeZ    Texpresso search in the literature
Synonym(s): ECK2428, G7268, b2433
Genome position(nucleotides): 2551277 <-- 2551726
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.89
External database links:  
ASAP:
 ABE-0008023
ECHOBASE:
 EB3919
ECOLIHUB:
 yfeZ
OU-MICROARRAY:
 b2433
STRING:
 511145.b2433
COLOMBOS: yfeZ


Product      
Name: putative inner membrane protein
Synonym(s): YfeZ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 17.168
Isoelectric point: 9.663
Motif(s):
 
Type Positions Sequence Comment
6 -> 145 FHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASREQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRATFPRTWRVLYFLLLLAQVVLLCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFY
19 -> 39 LPLLFWLVLLLQARTWVLFVI UniProt: Helical.
59 -> 79 DNFWLGLIPGIPAVLAFLLSG UniProt: Helical.
90 -> 110 VLYFLLLLAQVVLLCWQPWLW UniProt: Helical.
116 -> 136 VSGIGLALVVADIVALIWLLT UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P76538
DIP:
 DIP-12023N
ECOCYC:
 G7268-MONOMER
ECOLIWIKI:
 b2433
INTERPRO:
 IPR021318
PFAM:
 PF11143
PRIDE:
 P76538
REFSEQ:
 NP_416928
SMR:
 P76538
UNIPROT:
 P76538


Operon      
Name: ypeA-yfeZ         
Operon arrangement:
Transcription unit        Promoter
ypeA-yfeZ


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yfeXp5 2550678 reverse nd [COMP-AINF] [1]
  promoter yfeZp3 2551921 reverse nd [COMP-AINF] [1]
  promoter TSS_2747 (cluster) 2552242 forward nd [RS-EPT-CBR] [2]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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