RegulonDB RegulonDB 11.0: Gene Form
   

hyfE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

hyfF hyfD hyfE hyfG

Gene      
Name: hyfE    Texpresso search in the literature
Synonym(s): ECK2481, G7302, b2485
Genome position(nucleotides): 2606262 --> 2606912
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.3
External database links:  
ASAP:
ABE-0008188
ECHOBASE:
EB3965
ECOLIHUB:
hyfE
OU-MICROARRAY:
b2485
STRING:
511145.b2485
COLOMBOS: hyfE


Product      
Name: hydrogenase 4 component E
Synonym(s): HyfE
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 23.361
Isoelectric point: 9.37
Motif(s):
 
Type Positions Sequence Comment
4 -> 24 SMIVNNLAGLMMLTSLFVISV UniProt: Helical.
39 -> 59 LVLVSIFATLSCLFAAEQLLI UniProt: Helical.
60 -> 80 WSASAFITKVLLVPLIMTYAA UniProt: Helical.
93 -> 113 FGPAMMALLAALIVLLCAFVV UniProt: Helical.
123 -> 143 GLKPALAVALGHFLLGLLCIV UniProt: Helical.

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0009326 - formate dehydrogenase complex
GO:0044569 - [Ni-Fe] hydrogenase complex
molecular_function GO:0016491 - oxidoreductase activity
biological_process GO:0006007 - glucose catabolic process
GO:0009061 - anaerobic respiration
GO:0019645 - anaerobic electron transport chain
GO:0015944 - formate oxidation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
P0AEW1
DIP:
DIP-48020N
ECOCYC:
MONOMER0-142
ECOLIWIKI:
b2485
INTERPRO:
IPR038730
INTERPRO:
IPR039428
PANTHER:
PTHR38601
PFAM:
PF00420
PRIDE:
P0AEW1
PRODB:
PRO_000022967
REFSEQ:
NP_416980
UNIPROT:
P0AEW1


Operon      
Name: hyfABCDEFGHIJR-focB         
Operon arrangement:
Transcription unit        Promoter
hyfABCDEFGHIJR-focB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FhlA, HyfR
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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