RegulonDB RegulonDB 11.1: Gene Form
   

hyfF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

hyfG hyfF hyfE hyfH hyfI

Gene      
Name: hyfF    Texpresso search in the literature
Synonym(s): ECK2482, G7303, b2486
Genome position(nucleotides): 2606917 --> 2608497
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.89
External database links:  
ASAP:
 ABE-0008191
ECHOBASE:
 EB3966
ECOLIHUB:
 hyfF
OU-MICROARRAY:
 b2486
STRING:
 511145.b2486
COLOMBOS: hyfF


Product      
Name: hydrogenase 4 component F
Synonym(s): HyfF
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 56.767
Isoelectric point: 8.39
Motif(s):
 
Type Positions Sequence Comment
4 -> 24 SVMFALLLLTPLLFSLLCFAC UniProt: Helical.
34 -> 54 TVTVLHSLGITLLLILALWVV UniProt: Helical.
70 -> 101 LHIDGLGGLFLAILGVIGFLTGIYSIGYMRHE
75 -> 95 LGGLFLAILGVIGFLTGIYSI UniProt: Helical.
122 -> 142 FLFTMLLVVTSNNLIVMWAAI UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0009326 - formate dehydrogenase complex
GO:0044569 - [Ni-Fe] hydrogenase complex
molecular_function GO:0016491 - oxidoreductase activity
biological_process GO:0006007 - glucose catabolic process
GO:0006974 - cellular response to DNA damage stimulus
GO:0009061 - anaerobic respiration
GO:0019645 - anaerobic electron transport chain
GO:0015944 - formate oxidation
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P77437
ECOCYC:
 MONOMER0-143
ECOLIWIKI:
 b2486
INTERPRO:
 IPR001516
INTERPRO:
 IPR001750
PFAM:
 PF00361
PFAM:
 PF00662
PRIDE:
 P77437
PRODB:
 PRO_000022968
REFSEQ:
 NP_416981
UNIPROT:
 P77437


Operon      
Name: hyfABCDEFGHIJR-focB         
Operon arrangement:
Transcription unit        Promoter
hyfABCDEFGHIJR-focB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FhlA, HyfR
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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