RegulonDB RegulonDB 11.1: Gene Form
   

hyfI gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

hyfR hyfG hyfI hyfH hyfJ hyfF

Gene      
Name: hyfI    Texpresso search in the literature
Synonym(s): ECK2485, G7306, b2489
Genome position(nucleotides): 2610706 --> 2611464
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.73
Reference(s): [1] Andrews SC., et al., 1997
External database links:  
ASAP:
 ABE-0008198
ECHOBASE:
 EB3969
ECOLIHUB:
 hyfI
OU-MICROARRAY:
 b2489
STRING:
 511145.b2489
COLOMBOS: hyfI


Product      
Name: hydrogenase 4 catalytic subunit HyfI
Synonym(s): HyfI, hydrogenase 4, small subunit
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 28.101
Isoelectric point: 8.083
Motif(s):
 
Type Positions Sequence Comment
44 -> 151 CNACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDHKICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHG

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.7 - anaerobic respiration
Gene Ontology Terms (GO)  
cellular_component GO:0005886 - plasma membrane
molecular_function GO:0046872 - metal ion binding
GO:0016491 - oxidoreductase activity
GO:0051536 - iron-sulfur cluster binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0008137 - NADH dehydrogenase (ubiquinone) activity
GO:0048038 - quinone binding
biological_process GO:0022900 - electron transport chain
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P77668
ECOCYC:
 MONOMER0-151
ECOLIWIKI:
 b2489
INTERPRO:
 IPR006137
INTERPRO:
 IPR006138
MODBASE:
 P77668
PFAM:
 PF01058
PRIDE:
 P77668
PROSITE:
 PS01150
REFSEQ:
 NP_416984
SMR:
 P77668
UNIPROT:
 P77668


Operon      
Name: hyfABCDEFGHIJR-focB         
Operon arrangement:
Transcription unit        Promoter
hyfABCDEFGHIJR-focB


Transcriptional Regulation      
Display Regulation             
Activated by: FhlA, CRP, HyfR
Repressed by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Andrews SC., Berks BC., McClay J., Ambler A., Quail MA., Golby P., Guest JR., 1997, A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system., Microbiology 143 ( Pt 11):3633-47

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