RegulonDB

Gene
Name:	ygaZ
Synonym(s):	ECK2676, G7405, b2682
Genome position(nucleotides):	2809617 --> 2810354 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.85
External database links:

ASAP:	ABE-0008829
ECHOBASE:	EB3299
ECOLIHUB:	ygaZ
OU-MICROARRAY:	b2682
STRING:	511145.b2682
COLOMBOS:	ygaZ

Product

Name:

L-valine exporter, YgaZ component

Synonym(s):

YgaZ, YgaZ L-valine LIV-E exporter

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

26.108

Isoelectric point:

8.492

Motif(s):

Type	Positions	Sequence
	25 -> 45	IVISYIPVAFAFGLNATRLGF
	110 -> 130	TALWAFGLTDEVFAAATAKLV
	24 -> 165	PIVISYIPVAFAFGLNATRLGFSPLESVFFSCIIYAGASQFVITAMLAAGSSLWIAALTVMAMDVRHVLYGPSLRSRIIQRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGAFSGSG
	64 -> 84	FVITAMLAAGSSLWIAALTVM
	141 -> 161	MIGIAFSSWSSWVFGTVIGAF

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		4 - transport
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0015562 - efflux transmembrane transporter activity GO:0005304 - L-valine transmembrane transporter activity
	biological_process	GO:1903785 - L-valine transmembrane transport

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PANTHER:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

ygaZH

Operon arrangement:

Transcription unit	Promoter
ygaZH

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_2993	2809569	forward	nd	[RS-EPT-CBR]	[1]
promoter	ygaZp8	2809595	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 5.156. P-value: 1.980e-5 Read more >	[ICWHO]	[2]
promoter	TSS_2994	2809748	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2995	2809756	forward	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78