RegulonDB RegulonDB 10.8: Gene Form
   

gudP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gudP gudX yqcA anti-terminator terminator gudDp1 gudDp1

Gene      
Name: gudP    Texpresso search in the literature
Synonym(s): ECK2783, G7447, b2789, gudT, ygcZ
Genome position(nucleotides): 2920748 <-- 2922100 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.25
External database links:  
ASAP:
 ABE-0009139
ECHOBASE:
 EB2961
OU-MICROARRAY:
 b2789
PortEco:
 gudP
STRING:
 511145.b2789
COLOMBOS: gudP


Product      
Name: galactarate/D-glucarate transporter GudP
Synonym(s): GudP, GudT, YgcZ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 49.142
Isoelectric point: 9.78
Motif(s):
 
Type Positions Sequence
330 -> 350 IVMGMLLSMVMVFCNYVNVEW
21 -> 41 IVVMLFIVTSFNYGDRATLSI
352 -> 372 IIGFMALAFFGKGIGALGWAV
417 -> 437 ALIYVGVHALIAVLSYLVLVG
25 -> 318 LFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRR

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
GO:0015296 - anion:cation symporter activity
biological_process GO:0019580 - galactarate metabolic process
GO:0042836 - D-glucarate metabolic process
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Hubbard BK., et al., 1998
[2] Moraes TF., et al., 2012
External database links:  
ECOCYC:
 B2789-MONOMER
ECOLIWIKI:
 b2789
INTERPRO:
 IPR011701
INTERPRO:
 IPR036259
INTERPRO:
 IPR020846
INTERPRO:
 IPR000849
MODBASE:
 Q46916
PFAM:
 PF07690
PRIDE:
 Q46916
PROSITE:
 PS50850
REFSEQ:
 NP_417269
SMR:
 Q46916
UNIPROT:
 Q46916


Operon      
Name: gudPXD         
Operon arrangement:
Transcription unit        Promoter
gudPXD


Transcriptional Regulation      
Display Regulation             
Activated by: CdaR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter gudDp1 2919513 reverse Similarity to the consensus
Read more > 		[ICWHO] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Hubbard BK., Koch M., Palmer DR., Babbitt PC., Gerlt JA., 1998, Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli., Biochemistry 37(41):14369-75

 [2] Moraes TF., Reithmeier RA., 2012, Membrane transport metabolons., Biochim Biophys Acta 1818(11):2687-706

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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