RegulonDB RegulonDB 10.10: Gene Form
   

dcuD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

dcuD nanR sspB rpsI3\' PhoP IHF dcuDp dcuDp nanRp9 nanRp9 nanRp10 nanRp10 dcuDp2 dcuDp2

Gene      
Name: dcuD    Texpresso search in the literature
Synonym(s): ECK3216, G7679, b3227, yhcL
Genome position(nucleotides): 3374869 --> 3376236 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.02
External database links:  
ASAP:
 ABE-0010589
ECHOBASE:
 EB2669
ECOLIHUB:
 dcuD
OU-MICROARRAY:
 b3227
STRING:
 511145.b3227
COLOMBOS: dcuD


Product      
Name: putative transporter DcuD
Synonym(s): DcuD, YhcL
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 48.831
Isoelectric point: 9.37
Motif(s):
 
Type Positions Sequence
26 -> 46 VVLAAAGIFLMMCGVWLGFGG
270 -> 290 ELHLVVVMLLSLTVTMFVEFF
348 -> 368 LGGIGVMIIMALVIAICAIVM
378 -> 398 FASLIPNIAAGLHVPAVVMIM
190 -> 210 ATYFFHYQLPVASCVIISVAI

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015556 - C4-dicarboxylate transmembrane transporter activity
biological_process GO:0015740 - C4-dicarboxylate transport
GO:0019588 - anaerobic glycerol catabolic process
Note(s): Note(s): ...[more].
Reference(s): [1] Mikoyan G., et al., 2020
External database links:  
DIP:
 DIP-9412N
ECOCYC:
 YHCL-MONOMER
ECOLIWIKI:
 b3227
INTERPRO:
 IPR004669
INTERPRO:
 IPR018385
PANTHER:
 PTHR42002
PFAM:
 PF03606
PRIDE:
 P45428
REFSEQ:
 NP_417694
UNIPROT:
 P45428


Operon      
Name: dcuD         
Operon arrangement:
Transcription unit        Promoter
dcuD
dcuD


Transcriptional Regulation      
Display Regulation             
Activated by: IHF
Repressed by: PhoP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter nanRp10 3374676 reverse nd [ICWHO] [2]
  promoter nanRp9 3374703 reverse nd [ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Mikoyan G., Karapetyan L., Vassilian A., Trchounian A., Trchounian K., 2020, External succinate and potassium ions influence Dcu dependent FO F1 -ATPase activity and H+ flux of Escherichia coli at different pHs., J Bioenerg Biomembr 52(5):377-382

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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