RegulonDB RegulonDB 10.9: Gene Form
   

hofM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mrcA hofM hofN hofO hofP CRP CRP terminator TSS_3995 TSS_3995 hofMp hofMp mrcAp mrcAp

Gene      
Name: hofM    Texpresso search in the literature
Synonym(s): ECK3382, G7739, b3395, yrfD
Genome position(nucleotides): 3521972 <-- 3522751 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
57.69
External database links:  
ASAP:
ABE-0011079
ECHOBASE:
EB2761
ECOLIHUB:
hofM
OU-MICROARRAY:
b3395
STRING:
511145.b3395
COLOMBOS: hofM


Product      
Name: DNA utilization protein HofM
Synonym(s): HofM, YrfD, protein involved in utilization of DNA as a carbon source
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 29.0
Isoelectric point: 7.044
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization
Gene Ontology Terms (GO)  
biological_process GO:0006308 - DNA catabolic process
GO:0015976 - carbon utilization
Note(s): Note(s): ...[more].
Evidence: [IMP] Inferred from mutant phenotype
Reference(s): [1] Palchevskiy V., et al., 2006
External database links:  
DIP:
DIP-12921N
ECOCYC:
G7739-MONOMER
ECOLIWIKI:
b3395
INTERPRO:
IPR043129
PRIDE:
P45753
REFSEQ:
NP_417854
UNIPROT:
P45753


Operon      
Name: hofMNOP         
Operon arrangement:
Transcription unit        Promoter
hofMNOP


Transcriptional Regulation      
Display Regulation             
Activated by: CRP


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3995 3524342 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Palchevskiy V., Finkel SE., 2006, Escherichia coli Competence Gene Homologs Are Essential for Competitive Fitness and the Use of DNA as a Nutrient., J Bacteriol 188(11):3902-10

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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