RegulonDB RegulonDB 10.9: Gene Form
   

yrfG gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

igaA yrfG hslR hslOp3 hslOp3 hslOp4 hslOp4 TSS_3998 (cluster) TSS_3998 (cluster) hslRp hslRp TSS_3997 TSS_3997

Gene      
Name: yrfG    Texpresso search in the literature
Synonym(s): ECK3386, G7742, b3399
Genome position(nucleotides): 3528669 --> 3529337 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.57
External database links:  
ASAP:
ABE-0011092
ECHOBASE:
EB2764
ECOLIHUB:
yrfG
OU-MICROARRAY:
b3399
STRING:
511145.b3399
COLOMBOS: yrfG


Product      
Name: purine nucleotidase
Synonym(s): YrfG
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 25.399
Isoelectric point: 4.927
Motif(s):
 
Type Positions Sequence
13 -> 190 VLLDMDGTLLDLAFDNYFWQKLVPETWGAKNGVTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFLEALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAEATGLKAERTLFIDDSEAILDAAAQFGIRYC
9 -> 11 DVD

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding
GO:0008253 - 5'-nucleotidase activity
GO:0050483 - IMP 5'-nucleotidase activity
GO:0050484 - GMP 5'-nucleotidase activity
GO:0008967 - phosphoglycolate phosphatase activity
GO:0008477 - purine nucleosidase activity
GO:0000287 - magnesium ion binding
GO:0030145 - manganese ion binding
biological_process GO:0006281 - DNA repair
GO:0016311 - dephosphorylation
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
G7742-MONOMER
ECOLIWIKI:
b3399
INTERPRO:
IPR041492
INTERPRO:
IPR036412
INTERPRO:
IPR023214
INTERPRO:
IPR006439
MODBASE:
P64636
PFAM:
PF13419
PRIDE:
P64636
PRINTS:
PR00413
REFSEQ:
NP_417858
SMR:
P64636
UNIPROT:
P64636


Operon      
Name: yrfG-hslRO         
Operon arrangement:
Transcription unit        Promoter
hslR-hslO
yrfG-hslR
hslO


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3997 3527462 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3998 (cluster) 3529665 forward For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter hslOp4 3529672 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter hslOp3 3529733 forward Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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