RegulonDB RegulonDB 10.10: Gene Form
   

ulaA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ulaA ulaG ulaB UlaR UlaR CRP UlaR UlaR ulaAp ulaAp ulaGp ulaGp ulaRp5 ulaRp5

Gene      
Name: ulaA    Texpresso search in the literature
Synonym(s): ECK4189, G7856, b4193, sgaT, yjfS
Genome position(nucleotides): 4419980 --> 4421377 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.08
Reference(s): [1] Yew WS., et al., 2002
External database links:  
ASAP:
 ABE-0013723
ECHOBASE:
 EB2386
ECOLIHUB:
 ulaA
OU-MICROARRAY:
 b4193
STRING:
 511145.b4193
COLOMBOS: ulaA


Product      
Name: L-ascorbate specific PTS enzyme IIC component
Synonym(s): SgaT, UlaA, YjfS
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 50.737
Isoelectric point: 7.702
Motif(s):
 
Type Positions Sequence
263 -> 283 VHWTVYILQTGFSFAVAIFII
451 -> 465 RAEEDAEKQLAEQSA
316 -> 336 AAIYSFAPNAVVWGFMWGTIG
101 -> 121 YSWVGYAVLLALALNICYVLL
379 -> 399 AALKICLVMGMIEIFGCVWAV

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.4 - Group Translocators --> 4.4.A - Phosphotransferase Systems (PEP-dependent PTS)
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0042802 - identical protein binding
GO:0090585 - protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0015882 - L-ascorbic acid transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Yew WS., et al., 2002
External database links:  
DIP:
 DIP-10870N
ECOCYC:
 SGAT-MONOMER
ECOLIWIKI:
 b4193
INTERPRO:
 IPR004703
PDB:
 4RP9
PDB:
 4RP8
PFAM:
 PF03611
PRIDE:
 P39301
PRODB:
 PRO_000024175
REFSEQ:
 NP_418614
SMR:
 P39301
UNIPROT:
 P39301


Operon      
Name: ulaABCDEF         
Operon arrangement:
Transcription unit        Promoter
ulaABCDEF


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: UlaR, IHF


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ulaRp5 4418562 reverse nd [ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Yew WS., Gerlt JA., 2002, Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons., J Bacteriol 184(1):302-6

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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