RegulonDB RegulonDB 10.9: Gene Form
   

xapA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

xapB xapA yfeN XapR XapR terminator xapAp xapAp xapBp3 xapBp3 xapBp2 xapBp2 xapBp xapBp

Gene      
Name: xapA    Texpresso search in the literature
Synonym(s): ECK2401, G85, b2407, pndA
Genome position(nucleotides): 2524045 <-- 2524878 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.68
External database links:  
ASAP:
 ABE-0007927
CGSC:
 9
ECHOBASE:
 EB4152
ECOLIHUB:
 xapA
MIM:
 613179
NCBI-GENE:
 946878
OU-MICROARRAY:
 b2407
STRING:
 511145.b2407
COLOMBOS: xapA


Shine dalgarno      
Sequence: ccctacagaaAAAGGAtatgTAT


Product      
Name: xanthosine phosphorylase
Synonym(s): PndA, XapA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 29.835
Isoelectric point: 6.504
Motif(s):
 
Type Positions Sequence
191 -> 191 Y
27 -> 274 RVAFILGSGLGALADQIENAVAISYEKLPGFPVSTVHGHAGELVLGHLQGVPVVCMKGRGHFYEGRGMTIMTDAIRTFKLLGCELLFCTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDDRFGERFFSLANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVVPEVISARHCDLKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLR
144 -> 144 P
265 -> 265 F
239 -> 239 N

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.33 - nucleotide and nucleoside conversions
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016757 - transferase activity, transferring glycosyl groups
GO:0016740 - transferase activity
GO:0004731 - purine-nucleoside phosphorylase activity
GO:0016763 - transferase activity, transferring pentosyl groups
GO:0047724 - inosine nucleosidase activity
GO:0042802 - identical protein binding
GO:0047975 - guanosine phosphorylase activity
biological_process GO:0006139 - nucleobase-containing compound metabolic process
GO:0009116 - nucleoside metabolic process
GO:0015949 - nucleobase-containing small molecule interconversion
GO:0006152 - purine nucleoside catabolic process
GO:0055086 - nucleobase-containing small molecule metabolic process
GO:0034355 - NAD salvage
GO:0006148 - inosine catabolic process
GO:0006149 - deoxyinosine catabolic process
GO:0006161 - deoxyguanosine catabolic process
GO:0034214 - protein hexamerization
GO:0046115 - guanosine catabolic process
GO:1903228 - xanthosine catabolic process
External database links:  
ECOCYC:
 XANTHOSINEPHOSPHORY-MONOMER
ECOLIWIKI:
 b2407
INTERPRO:
 IPR018099
INTERPRO:
 IPR011268
INTERPRO:
 IPR010943
INTERPRO:
 IPR035994
INTERPRO:
 IPR000845
MODBASE:
 P45563
PANTHER:
 PTHR11904
PDB:
 1YR3
PDB:
 1YQU
PDB:
 1YQQ
PFAM:
 PF01048
PRIDE:
 P45563
PRODB:
 PRO_000024228
PROSITE:
 PS01240
REFSEQ:
 NP_416902
SMR:
 P45563
UNIPROT:
 P45563


Operon      
Name: xapAB         
Operon arrangement:
Transcription unit        Promoter
xapB
xapB
xapB
xapAB
xapAB


Transcriptional Regulation      
Display Regulation             
Activated by: XapR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB