RegulonDB RegulonDB 11.1: Gene Form
   

ymgF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ycgH pdeG ymgD ymgF ymgFp10 ymgFp10 ymgFp11 ymgFp11 ymgFp7 ymgFp7 ymgFp1 ymgFp1

Gene      
Name: ymgF    Texpresso search in the literature
Synonym(s): ECK1156, G0-10261, b4520
Genome position(nucleotides): 1218983 --> 1219201
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 40.18
External database links:  
ASAP:
 ABE-0285041
ECHOBASE:
 EB4087
ECOLIHUB:
 ymgF
STRING:
 511145.b4520
COLOMBOS: ymgF


Product      
Name: inner membrane protein YmgF
Synonym(s): YmgF, inner membrane protein that interacts with cell division proteins
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 8.255
Isoelectric point: 9.151
Motif(s):
 
Type Positions Sequence Comment
10 -> 30 FTLYIIFSIAFMLITLLVILI UniProt: Helical.
35 -> 55 TGLGEVLVTINLLNALVWLAI UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.1 - cell division
Gene Ontology Terms (GO)  
cellular_component GO:0000935 - division septum
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
biological_process GO:0051301 - cell division
GO:0007049 - cell cycle
Note(s): Note(s): ...[more].
Evidence: [EXP-IGI] Inferred from genetic interaction
[EXP-IPI] Inferred from physical interaction
Reference(s): [1] Karimova G., et al., 2005
[2] Karimova G., et al., 2012
[3] Karimova G., et al., 2009
[4] Lies M., et al., 2015
External database links:  
ALPHAFOLD:
 P58034
DIP:
 DIP-12735N
ECOCYC:
 MONOMER0-2141
ECOLIWIKI:
 b4520
PRIDE:
 P58034
REFSEQ:
 YP_588447
UNIPROT:
 P58034


Operon      
Name: ymgF         
Operon arrangement:
Transcription unit        Promoter
ymgF


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ymgFp1 1218814 forward nd [COMP-AINF] [5]
  promoter ymgFp7 1218937 forward nd [COMP-AINF] [5]
  promoter ymgFp11 1218940 forward nd [COMP-AINF] [5]
  promoter ymgFp10 1218953 forward nd [COMP-AINF] [5]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Karimova G., Dautin N., Ladant D., 2005, Interaction network among Escherichia coli membrane proteins involved in cell division as revealed by bacterial two-hybrid analysis., J Bacteriol 187(7):2233-43

 [2] Karimova G., Davi M., Ladant D., 2012, The β-lactam resistance protein Blr, a small membrane polypeptide, is a component of the Escherichia coli cell division machinery., J Bacteriol 194(20):5576-88

 [3] Karimova G., Robichon C., Ladant D., 2009, Characterization of YmgF, a 72-residue inner membrane protein that associates with the Escherichia coli cell division machinery., J Bacteriol 191(1):333-46

 [4] Lies M., Visser BJ., Joshi MC., Magnan D., Bates D., 2015, MioC and GidA proteins promote cell division in E. coli., Front Microbiol 6:516

 [5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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