RegulonDB RegulonDB 10.9: Gene Form
   

cpxQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fieF cpxP cpxQ terminator TSS_4600 (cluster) TSS_4600 (cluster) fieFp4 fieFp4 fieFp3 fieFp3 TSS_4598 TSS_4598 TSS_4597 TSS_4597 TSS_4596 TSS_4596

Gene      
Name: cpxQ    Texpresso search in the literature
Synonym(s): ECK4573, G0-16649, b4716
Genome position(nucleotides): 4106330 --> 4106387 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.28


Product      
Name: small regulatory RNA CpxQ
Synonym(s): CpxQ
Type: small RNA
Classification:
Multifun Terms (GenProtEC)  
  3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional
Gene Ontology Terms (GO)  
biological_process GO:0036460 - cellular response to cell envelope stress
Note(s): Note(s): ...[more].
Evidence: [IGI] Inferred from genetic interaction
[IMP] Inferred from mutant phenotype
Reference(s): [1] Grabowicz M., et al., 2016
External database links:  
ECOCYC:
RNA0-389


Operon      
Name: cpxPQ         
Operon arrangement:
Transcription unit        Promoter
cpxPQ


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4596 4106222 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4597 4106224 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4598 4106290 forward nd [RS-EPT-CBR] [2]
  promoter fieFp3 4106432 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter fieFp4 4106449 forward Similarity to the consensus
Read more >
[ICWHO], [RS-EPT-CBR] [2], [3]
  promoter TSS_4600 (cluster) 4107207 forward For this promoter, there
Read more >
[RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Grabowicz M., Koren D., Silhavy TJ., 2016, The CpxQ sRNA Negatively Regulates Skp To Prevent Mistargeting of β-Barrel Outer Membrane Proteins into the Cytoplasmic Membrane., MBio 7(2):e00312-16

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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