RegulonDB RegulonDB 11.1: Gene Form
   

gndA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gnd ugd insH7 gndA anti-anti-terminator anti-terminator terminator anti-anti-terminator anti-terminator TSS_2378 TSS_2378 TSS_2377 TSS_2377 TSS_2376 TSS_2376 gndp gndp TSS_2374 TSS_2374 TSS_2373 (cluster) TSS_2373 (cluster) TSS_2372 (cluster) TSS_2372 (cluster) TSS_2371 TSS_2371 TSS_2370 TSS_2370 TSS_2369 TSS_2369 TSS_2368 TSS_2368 ugdp9 ugdp9 cldp10 cldp10

Gene      
Name: gndA    Texpresso search in the literature
Synonym(s): G0-16693
Genome position(nucleotides): 2100863 <-- 2101027
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 47.88


Product      
Name: heat shock-induced protein GndA
Synonym(s): GndA
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 5.956
Isoelectric point: 12.515
Motif(s):
 
Type Positions Sequence Comment
28 -> 50 LFVVIVSFQQRALTSSVPVFLAV UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
biological_process GO:0034605 - cellular response to heat
Note(s): Note(s): ...[more].
Reference(s): [1] Yuan P., et al., 2018
External database links:  
ALPHAFOLD:
 P0DQD7
ECOCYC:
 MONOMER0-4397
SMR:
 P0DQD7
UNIPROT:
 P0DQD7


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter cldp10 2098475 reverse nd [COMP-AINF] [2]
  promoter ugdp9 2099735 reverse nd [COMP-AINF] [2]
  promoter TSS_2368 2100229 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2369 2100231 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2370 2100277 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2371 2101069 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2372 (cluster) 2101178 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2373 (cluster) 2101320 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2374 2101322 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2376 2101396 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2377 2101409 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_2378 2101436 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Yuan P., D'Lima NG., Slavoff SA., 2018, Comparative Membrane Proteomics Reveals a Nonannotated E. coli Heat Shock Protein., Biochemistry 57(1):56-60

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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