RegulonDB RegulonDB

PdhR Genetic Sensory Response Unit in Escherichia coli K-12 genome


Gensor Unit Map          
FPP D-lactate D-lactate_Ext L-lactate L-lactate_Ext L-malate 2-(alpha-hydroxyethyl)-TPP ketoglutarate 5'-deoxyadenosine 5,10-methylenetetrahydrofolate L-alanine AceE AceF CO2 Cu(I) Cu(II) CyoA CyoB CyoC CyoD CyoE D-ala D-alanyl-D-alanine D-glu DdlB ExbB ExbD FecA FecB FecC FecD FecE FtsA FtsI FtsL FtsQ FtsW FtsZ GcvH GcvP GcvT GlcA GlcB GlcD GlcE GlcF GlcG GrcA HemL Hha L-alanine L-methionine LipA Lpd LpxC MraY MraZ MurC MurD MurE MurF MurG N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine_Ext N4-methylcytidine1402 in 16S rRNA Ndh PdhR pyruvate RsmH S-adenosyl-L-homocysteine S-adenosyl-L-methionine sulfur(2-) SucA SucB TomB TonB Udp UDP-3-O-(3-hydroxytetradecanoyl)glucosamine UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine UDP-GlcNAc UDP-N-acetylmuramoyl-L-alanyl-D-glutamate UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine UDP-N-acetylmuramyl-L-Ala UDP-N-alpha-D-acetylmuramate UMP a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine an enzyme N6-(dihydrolipoyl)lysine an enzyme N6-(lipoyl)lysine a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine an [enzyme] N6-(dihydrolipoyl)lysine lipoyl-domain an octanoylated protein lipoyl-domain an [enzyme] N6-(S-acetyldihydrolipoyl)lysine a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine a peptidoglycan dimer (meso-diaminopimelate containing) a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) a reduced electron acceptor acetate ac-CoA ammonia an oxidized electron acceptor an ubiquinol an ubiquinol_Ext ubiquinone CoA cyoABCDE cyoABCDE_mRNA cytidine1402 in 16S rRNA UPP (ambiguous) ditrans,polycis-undecaprenyl phosphate PP fecABCDE fecABCDE_mRNA iron dicitrate iron dicitrate_Ext glcDEFGBA glcDEFGBA_mRNA glutamate-1-semialdehyde glycine glycolate glycolate_Ext glyoxylate grcA grcA_mRNA hemL hemL_mRNA heme o lipA lipA_mRNA M-DAP mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA ndh ndh_mRNA oxygen_Ext pdhR-aceEF-lpd pdhR-aceEF-lpd_mRNA peptidoglycan D-alanyl-DAP crosslink peptidoglycan tetrapeptide, glycan chain 1 peptidoglycan tetrapeptide, glycan chain 2 phosphate protoheme IX pyruvate suc-coa THF TDP tomB-hha tomB-hha_mRNA PdhR pyruvate FecB FecD FecC FecE TonB ExbB ExbD FecA FecE FecC FecD FecB AceE AceF Lpd CyoD CyoA CyoB CyoC FecA ExbD ExbB TonB Lpd GcvP GcvH GcvT SucA SucB Lpd GlcD GlcE GlcF phosphate phosphate phosphate phosphate phosphate D-ala CO2 CO2 CO2 CO2 CO2 pyruvate pyruvate an [enzyme] N6-(S-acetyldihydrolipoyl)lysine an [enzyme] N6-(S-acetyldihydrolipoyl)lysine CO2 CoA CoA CoA a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine 2-(alpha-hydroxyethyl)-TPP TDP glyoxylate suc-coa lipoyl-domain ammonia THF


Gensor Unit       
Name: PdhR
Classification:
Groups: Inorganic ion transport and metabolism
Transcription
Energy production and conversion
Coenzyme transport and metabolism
Cell wall/membrane/envelope biogenesis
Cell cycle control, cell division, chromosome partitioning
Translation, ribosomal structure and biogenesis
Gene Ontology Terms (GO): biological_process GO:0006103 - 2-oxoglutarate metabolic process
GO:0042773 - ATP synthesis coupled electron transport
GO:0043093 - FtsZ-dependent cytokinesis
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0019646 - aerobic electron transport chain
GO:0009060 - aerobic respiration
Read more >
cellular_component GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:0030964 - NADH dehydrogenase complex
GO:0032153 - cell division site
GO:0009279 - cell outer membrane
GO:0009319 - cytochrome o ubiquinol oxidase complex
GO:0005737 - cytoplasm
GO:0009898 - cytoplasmic side of plasma membrane
Read more >
molecular_function GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0005524 - ATP binding
GO:0016887 - ATP hydrolysis activity
GO:0042626 - ATPase-coupled transmembrane transporter activity
GO:0008716 - D-alanine-D-alanine ligase activity
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
Read more >
Components:
  Function Name Type
  simple_molecule 2-(α-hydroxyethyl)-TPP simple_molecule
  simple_molecule 2-hydroxybutyrate simple_molecule
  simple_molecule 2-hydroxybutyrate_Ext simple_molecule
  simple_molecule 5'-UMP simple_molecule
  simple_molecule 5-aminolevulinate simple_molecule
  simple_molecule A(H2) simple_molecule
  protein AceE protein
  complex AceE-AceF-Lpd complex
  protein AceF protein
  simple_molecule CO2 simple_molecule
  simple_molecule Cu(I) simple_molecule
  simple_molecule Cu(II) simple_molecule
  protein CyoA protein
  protein CyoB protein
  protein CyoC protein
  protein CyoD protein
  complex CyoD-CyoA-CyoB-CyoC complex
  protein CyoE protein
  protein DdlB protein
  protein ExbB protein
  protein ExbD protein
  protein FecA protein
  complex FecA-ExbD-ExbB-TonB complex
  complex FecA-FecR complex
  protein FecB protein
  protein FecC protein
  protein FecD protein
  protein FecE protein
  complex FecE-FecC-FecD-FecB complex
  protein FecR protein
  protein FtsA protein
  protein FtsB protein
  protein FtsI protein
  protein FtsL protein
  protein FtsQ protein
  complex FtsQ-FtsB-FtsL complex
  protein FtsW protein
  protein FtsZ protein
  protein GcvH protein
  protein GcvP protein
  protein GcvT protein
  protein GlcA protein
  protein GlcB protein
  protein GlcD protein
  complex GlcD-GlcE-GlcF complex
  protein GlcE protein
  protein GlcF protein
  protein GlcG protein
  protein GrcA protein
  protein HemL protein
  protein Hha protein
  protein Lpd protein
  complex Lpd-GcvP-GcvH-GcvT complex
  protein LpxC protein
  simple_molecule M-DAP simple_molecule
  protein MraY protein
  protein MraZ protein
  protein MurC protein
  protein MurD protein
  protein MurE protein
  protein MurF protein
  protein MurG protein
  simple_molecule N4-methylcytidine1402 in 16S rRNA simple_molecule
  protein Ndh protein
  simple_molecule P-enol-pyruvate simple_molecule
  protein PdhR protein
  complex PdhR-pyruvate complex
  protein RsmH protein
  simple_molecule SAM simple_molecule
  protein SucA protein
  complex SucA-SucB-Lpd complex
  protein SucB protein
  simple_molecule THF polyglutamate simple_molecule
  simple_molecule Te0 simple_molecule
  simple_molecule TeO2 simple_molecule
  simple_molecule ThPP simple_molecule
  protein TomB protein
  protein TonB protein
  simple_molecule UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine simple_molecule
  simple_molecule UDP-3-O-(3-hydroxytetradecanoyl)glucosamine simple_molecule
  simple_molecule UDP-GlcNAc simple_molecule
  simple_molecule UDP-MurNAc simple_molecule
  simple_molecule UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm simple_molecule
  simple_molecule UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate simple_molecule
  simple_molecule UDP-N-acetyl-α-D-muramyl-L-Ala simple_molecule
  simple_molecule UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine simple_molecule
  simple_molecule [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine simple_molecule
  simple_molecule [enzyme] N6-(S-acetyldihydrolipoyl)lysine simple_molecule
  simple_molecule [enzyme] N6-(dihydrolipoyl)lysine simple_molecule
  simple_molecule [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine simple_molecule
  simple_molecule [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine simple_molecule
  simple_molecule [glycine-cleavage complex H protein] N6-lipoyl-L-lysine simple_molecule
  simple_molecule [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine simple_molecule
  simple_molecule [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine simple_molecule
  simple_molecule acceptors simple_molecule
  simple_molecule acetate simple_molecule
  simple_molecule acetyl-CoA simple_molecule
  simple_molecule adenosylhomocysteine simple_molecule
  simple_molecule ala simple_molecule
  simple_molecule alanine simple_molecule
  simple_molecule alanyl-D-alanine simple_molecule
  simple_molecule ammonium simple_molecule
  simple_molecule coenzyme A simple_molecule
  gene cyoABCDE gene
  RNA cyoABCDE_mRNA RNA
  simple_molecule cytidine1402 in 16S rRNA simple_molecule
  simple_molecule diphosphate simple_molecule
  simple_molecule ditrans,polycis-undecaprenyl phosphate simple_molecule
  simple_molecule electron-transfer quinol simple_molecule
  simple_molecule electron-transfer quinone simple_molecule
  simple_molecule enzyme N6-(dihydrolipoyl)lysine simple_molecule
  simple_molecule enzyme N6-(lipoyl)lysine simple_molecule
  simple_molecule farnesyl-PP simple_molecule
  gene fecABCDE gene
  RNA fecABCDE_mRNA RNA
  simple_molecule ferroheme o simple_molecule
  gene glcDEFGBA gene
  RNA glcDEFGBA_mRNA RNA
  simple_molecule glu simple_molecule
  simple_molecule glutamate 1-semialdehyde simple_molecule
  simple_molecule glycine simple_molecule
  simple_molecule glycolate simple_molecule
  simple_molecule glycolate_Ext simple_molecule
  simple_molecule glyoxylate simple_molecule
  gene grcA gene
  RNA grcA_mRNA RNA
  gene hemL gene
  RNA hemL_mRNA RNA
  simple_molecule iron dicitrate simple_molecule
  simple_molecule iron dicitrate_Ext simple_molecule
  simple_molecule ketoglutarate simple_molecule
  simple_molecule lactate simple_molecule
  simple_molecule lactate_Ext simple_molecule
  simple_molecule lipid I simple_molecule
  simple_molecule lipid II simple_molecule
  simple_molecule lipoyl-domain simple_molecule
  simple_molecule malate simple_molecule
  simple_molecule menaquinol simple_molecule
  simple_molecule methylene-H4PteGlu(n) simple_molecule
  gene mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC gene
  RNA mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
  simple_molecule nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide simple_molecule
  simple_molecule nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) simple_molecule
  gene ndh gene
  RNA ndh_mRNA RNA
  simple_molecule oxygen_Ext simple_molecule
  gene pdhR-aceEF-lpd gene
  RNA pdhR-aceEF-lpd_mRNA RNA
  simple_molecule peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide simple_molecule
  simple_molecule phosphate simple_molecule
  simple_molecule protoheme IX simple_molecule
  simple_molecule pyruvate simple_molecule
  simple_molecule suc-coa simple_molecule
  gene tomB-hha gene
  RNA tomB-hha_mRNA RNA
  simple_molecule ubiquinol simple_molecule
  simple_molecule ubiquinol_Ext simple_molecule
  simple_molecule ubiquinone simple_molecule
  simple_molecule uridine-diphosphate simple_molecule
  simple_molecule vitamin K2 simple_molecule


Reactions       
Showing 104 reactions
PdhR fecABCDE fecABCDE_mRNA
Name: fecABCDE -> fecABCDE_mRNA
Description: Transcription of transcription unit fecABCDE. Reaction activation by PdhR.
Type: transcription
Pathway Components: fecABCDE - PdhR -> fecABCDE_mRNA
Components:
Function Name Type
activator PdhR protein
reactant fecABCDE gene
product fecABCDE_mRNA RNA
PdhR cyoABCDE cyoABCDE_mRNA
Name: cyoABCDE -> cyoABCDE_mRNA
Description: Transcription of transcription unit cyoABCDE. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: cyoABCDE - PdhR -> cyoABCDE_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant cyoABCDE gene
product cyoABCDE_mRNA RNA
PdhR glcDEFGBA glcDEFGBA_mRNA
Name: glcDEFGBA -> glcDEFGBA_mRNA
Description: Transcription of transcription unit glcDEFGBA. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: glcDEFGBA - PdhR -> glcDEFGBA_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant glcDEFGBA gene
product glcDEFGBA_mRNA RNA
PdhR grcA grcA_mRNA
Name: grcA -> grcA_mRNA
Description: Transcription of transcription unit grcA. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: grcA - PdhR -> grcA_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant grcA gene
product grcA_mRNA RNA
PdhR hemL hemL_mRNA
Name: hemL -> hemL_mRNA
Description: Transcription of transcription unit hemL. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: hemL - PdhR -> hemL_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant hemL gene
product hemL_mRNA RNA
PdhR mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC -> mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA
Description: Transcription of transcription unit mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC - PdhR -> mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC gene
product mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
PdhR ndh ndh_mRNA
Name: ndh -> ndh_mRNA
Description: Transcription of transcription unit ndh. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: ndh - PdhR -> ndh_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant ndh gene
product ndh_mRNA RNA
PdhR pdhR-aceEF-lpd pdhR-aceEF-lpd_mRNA
Name: pdhR-aceEF-lpd -> pdhR-aceEF-lpd_mRNA
Description: Transcription of transcription unit pdhR-aceEF-lpd. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: pdhR-aceEF-lpd - PdhR -> pdhR-aceEF-lpd_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant pdhR-aceEF-lpd gene
product pdhR-aceEF-lpd_mRNA RNA
PdhR tomB-hha tomB-hha_mRNA
Name: tomB-hha -> tomB-hha_mRNA
Description: Transcription of transcription unit tomB-hha. Reaction inhibition by PdhR.
Type: transcription
Pathway Components: tomB-hha - PdhR -> tomB-hha_mRNA
Components:
Function Name Type
inhibitor PdhR protein
reactant tomB-hha gene
product tomB-hha_mRNA RNA
pyruvate + PdhR PdhR-pyruvate
Name: pyruvate + PdhR -> PdhR-pyruvate
Description: Reaction transforming pyruvate, PdhR into PdhR-pyruvate
Type: state transition
Pathway Components: pyruvate + PdhR -> PdhR-pyruvate
Components:
Function Name Type
reactant PdhR protein
product PdhR-pyruvate complex
reactant pyruvate simple_molecule
glcDEFGBA_mRNA GlcD
Name: glcDEFGBA_mRNA -> GlcD
Description: Translation of GlcD
Type: translation
Pathway Components: glcDEFGBA_mRNA -> GlcD
Components:
Function Name Type
product GlcD protein
reactant glcDEFGBA_mRNA RNA
GlcD + GlcF + GlcE GlcD-GlcE-GlcF
Name: GlcD + GlcF + GlcE -> GlcD-GlcE-GlcF
Description: Reaction transforming GlcD, GlcF, GlcE into GlcD-GlcE-GlcF
Type: state transition
Pathway Components: GlcD + GlcF + GlcE -> GlcD-GlcE-GlcF
Components:
Function Name Type
reactant GlcD protein
product GlcD-GlcE-GlcF complex
reactant GlcE protein
reactant GlcF protein
GlcD-GlcE-GlcF acceptors + glycolate glyoxylate + A(H2)
Name: acceptors + glycolate -> glyoxylate + A(H2)
Description: Reaction transforming acceptors, glycolate into glyoxylate, A(H2)
Type: state transition
Pathway Components: acceptors + glycolate - GlcD-GlcE-GlcF -> glyoxylate + A(H2)
Components:
Function Name Type
product A(H2) simple_molecule
catalyzer GlcD-GlcE-GlcF complex
reactant acceptors simple_molecule
reactant glycolate simple_molecule
product glyoxylate simple_molecule
GlcD-GlcE-GlcF electron-transfer quinone + glycolate electron-transfer quinol + glyoxylate
Name: electron-transfer quinone + glycolate -> electron-transfer quinol + glyoxylate
Description: Reaction transforming electron-transfer quinone, glycolate into electron-transfer quinol, glyoxylate
Type: state transition
Pathway Components: electron-transfer quinone + glycolate - GlcD-GlcE-GlcF -> electron-transfer quinol + glyoxylate
Components:
Function Name Type
catalyzer GlcD-GlcE-GlcF complex
product electron-transfer quinol simple_molecule
reactant electron-transfer quinone simple_molecule
reactant glycolate simple_molecule
product glyoxylate simple_molecule
glcDEFGBA_mRNA GlcE
Name: glcDEFGBA_mRNA -> GlcE
Description: Translation of GlcE
Type: translation
Pathway Components: glcDEFGBA_mRNA -> GlcE
Components:
Function Name Type
product GlcE protein
reactant glcDEFGBA_mRNA RNA
glcDEFGBA_mRNA GlcF
Name: glcDEFGBA_mRNA -> GlcF
Description: Translation of GlcF
Type: translation
Pathway Components: glcDEFGBA_mRNA -> GlcF
Components:
Function Name Type
product GlcF protein
reactant glcDEFGBA_mRNA RNA
glcDEFGBA_mRNA GlcG
Name: glcDEFGBA_mRNA -> GlcG
Description: Translation of GlcG
Type: translation
Pathway Components: glcDEFGBA_mRNA -> GlcG
Components:
Function Name Type
product GlcG protein
reactant glcDEFGBA_mRNA RNA
glcDEFGBA_mRNA GlcB
Name: glcDEFGBA_mRNA -> GlcB
Description: Translation of GlcB
Type: translation
Pathway Components: glcDEFGBA_mRNA -> GlcB
Components:
Function Name Type
product GlcB protein
reactant glcDEFGBA_mRNA RNA
GlcB glycolate pyruvate acetyl-CoA + glyoxylate coenzyme A + malate
Name: acetyl-CoA + glyoxylate -> coenzyme A + malate
Description: Reaction transforming acetyl-CoA, glyoxylate into coenzyme A, malate
Type: state transition
Pathway Components: acetyl-CoA + glyoxylate - GlcB - glycolate - pyruvate -> coenzyme A + malate
Components:
Function Name Type
catalyzer GlcB protein
reactant acetyl-CoA simple_molecule
product coenzyme A simple_molecule
inhibitor glycolate simple_molecule
reactant glyoxylate simple_molecule
product malate simple_molecule
inhibitor pyruvate simple_molecule
glcDEFGBA_mRNA GlcA
Name: glcDEFGBA_mRNA -> GlcA
Description: Translation of GlcA
Type: translation
Pathway Components: glcDEFGBA_mRNA -> GlcA
Components:
Function Name Type
product GlcA protein
reactant glcDEFGBA_mRNA RNA
GlcA glycolate_Ext glycolate
Name: glycolate_Ext -> glycolate
Description: Transport of glycolate_Ext through a bacterial membrane, leading to the presence of glycolate inside the cell.
Type: transport
Pathway Components: glycolate_Ext - GlcA -> glycolate
Components:
Function Name Type
catalyzer GlcA protein
product glycolate simple_molecule
reactant glycolate_Ext simple_molecule
GlcA lactate_Ext lactate
Name: lactate_Ext -> lactate
Description: Transport of lactate_Ext through a bacterial membrane, leading to the presence of lactate inside the cell.
Type: transport
Pathway Components: lactate_Ext - GlcA -> lactate
Components:
Function Name Type
catalyzer GlcA protein
product lactate simple_molecule
reactant lactate_Ext simple_molecule
GlcA 2-hydroxybutyrate_Ext 2-hydroxybutyrate
Name: 2-hydroxybutyrate_Ext -> 2-hydroxybutyrate
Description: Transport of 2-hydroxybutyrate_Ext through a bacterial membrane, leading to the presence of 2-hydroxybutyrate inside the cell.
Type: transport
Pathway Components: 2-hydroxybutyrate_Ext - GlcA -> 2-hydroxybutyrate
Components:
Function Name Type
product 2-hydroxybutyrate simple_molecule
reactant 2-hydroxybutyrate_Ext simple_molecule
catalyzer GlcA protein
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MraZ
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MraZ
Description: Translation of MraZ
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MraZ
Components:
Function Name Type
product MraZ protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RsmH
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> RsmH
Description: Translation of RsmH
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> RsmH
Components:
Function Name Type
product RsmH protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
RsmH cytidine1402 in 16S rRNA + SAM Products
Name: cytidine1402 in 16S rRNA + SAM -> N4-methylcytidine1402 in 16S rRNA + adenosylhomocysteine
Description: Reaction transforming cytidine1402 in 16S rRNA, SAM into N4-methylcytidine1402 in 16S rRNA, adenosylhomocysteine
Type: state transition
Pathway Components: cytidine1402 in 16S rRNA + SAM - RsmH -> N4-methylcytidine1402 in 16S rRNA + adenosylhomocysteine
Components:
Function Name Type
product N4-methylcytidine1402 in 16S rRNA simple_molecule
catalyzer RsmH protein
reactant SAM simple_molecule
product adenosylhomocysteine simple_molecule
reactant cytidine1402 in 16S rRNA simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA FtsL
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsL
Description: Translation of FtsL
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsL
Components:
Function Name Type
product FtsL protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
FtsB + FtsQ + FtsL FtsQ-FtsB-FtsL
Name: FtsB + FtsQ + FtsL -> FtsQ-FtsB-FtsL
Description: Reaction transforming FtsB, FtsQ, FtsL into FtsQ-FtsB-FtsL
Type: state transition
Pathway Components: FtsB + FtsQ + FtsL -> FtsQ-FtsB-FtsL
Components:
Function Name Type
reactant FtsB protein
reactant FtsL protein
reactant FtsQ protein
product FtsQ-FtsB-FtsL complex
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA FtsI
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsI
Description: Translation of FtsI
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsI
Components:
Function Name Type
product FtsI protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
FtsI Reactants Products
Name: nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide -> nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + ala
Description: Reaction transforming nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide, peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide into nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing), ala
Type: state transition
Pathway Components: nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide - FtsI -> nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + ala
Components:
Function Name Type
catalyzer FtsI protein
product ala simple_molecule
reactant nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide simple_molecule
product nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) simple_molecule
reactant peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MurE
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurE
Description: Translation of MurE
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurE
Components:
Function Name Type
product MurE protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
MurE UDP-GlcNAc UDP-MurNAc UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm UDP-N-acetyl-α-D-muramyl-L-Ala uridine-diphosphate Reactants Products
Name: UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + M-DAP -> UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm + phosphate
Description: Reaction transforming UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate, M-DAP into UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm, phosphate
Type: state transition
Pathway Components: UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + M-DAP - MurE - UDP-GlcNAc - UDP-MurNAc - UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm - UDP-N-acetyl-α-D-muramyl-L-Ala - uridine-diphosphate -> UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm + phosphate
Components: Show/Hide Components Table
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MurF
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurF
Description: Translation of MurF
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurF
Components:
Function Name Type
product MurF protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
MurF Reactants Products
Name: UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm + alanyl-D-alanine -> UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + phosphate
Description: Reaction transforming UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm, alanyl-D-alanine into UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine, phosphate
Type: state transition
Pathway Components: UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm + alanyl-D-alanine - MurF -> UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + phosphate
Components:
Function Name Type
catalyzer MurF protein
reactant UDP-MurNAc-L-Ala-γ-D-Glu-meso-A2pm simple_molecule
product UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine simple_molecule
reactant alanyl-D-alanine simple_molecule
product phosphate simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MraY
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MraY
Description: Translation of MraY
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MraY
Components:
Function Name Type
product MraY protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
MraY Reactants lipid I + 5'-UMP
Name: UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ditrans,polycis-undecaprenyl phosphate -> lipid I + 5'-UMP
Description: Reaction transforming UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine, ditrans,polycis-undecaprenyl phosphate into lipid I, 5'-UMP
Type: state transition
Pathway Components: UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ditrans,polycis-undecaprenyl phosphate - MraY -> lipid I + 5'-UMP
Components:
Function Name Type
product 5'-UMP simple_molecule
catalyzer MraY protein
reactant UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine simple_molecule
reactant ditrans,polycis-undecaprenyl phosphate simple_molecule
product lipid I simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MurD
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurD
Description: Translation of MurD
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurD
Components:
Function Name Type
product MurD protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
MurD Inhibitor UDP-N-acetyl-α-D-muramyl-L-Ala + glu Products
Name: UDP-N-acetyl-α-D-muramyl-L-Ala + glu -> UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + phosphate
Description: Reaction transforming UDP-N-acetyl-α-D-muramyl-L-Ala, glu into UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate, phosphate
Type: state transition
Pathway Components: UDP-N-acetyl-α-D-muramyl-L-Ala + glu - MurD - UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate -> UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + phosphate
Components:
Function Name Type
catalyzer MurD protein
inhibitor UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate simple_molecule
product UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate simple_molecule
reactant UDP-N-acetyl-α-D-muramyl-L-Ala simple_molecule
reactant glu simple_molecule
product phosphate simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA FtsW
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsW
Description: Translation of FtsW
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsW
Components:
Function Name Type
product FtsW protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MurG
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurG
Description: Translation of MurG
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurG
Components:
Function Name Type
product MurG protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
MurG UDP-GlcNAc + lipid I uridine-diphosphate + lipid II
Name: UDP-GlcNAc + lipid I -> uridine-diphosphate + lipid II
Description: Reaction transforming UDP-GlcNAc, lipid I into uridine-diphosphate, lipid II
Type: state transition
Pathway Components: UDP-GlcNAc + lipid I - MurG -> uridine-diphosphate + lipid II
Components:
Function Name Type
catalyzer MurG protein
reactant UDP-GlcNAc simple_molecule
reactant lipid I simple_molecule
product lipid II simple_molecule
product uridine-diphosphate simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA MurC
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurC
Description: Translation of MurC
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> MurC
Components:
Function Name Type
product MurC protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
MurC UDP-MurNAc + alanine UDP-N-acetyl-α-D-muramyl-L-Ala + phosphate
Name: UDP-MurNAc + alanine -> UDP-N-acetyl-α-D-muramyl-L-Ala + phosphate
Description: Reaction transforming UDP-MurNAc, alanine into UDP-N-acetyl-α-D-muramyl-L-Ala, phosphate
Type: state transition
Pathway Components: UDP-MurNAc + alanine - MurC -> UDP-N-acetyl-α-D-muramyl-L-Ala + phosphate
Components:
Function Name Type
catalyzer MurC protein
reactant UDP-MurNAc simple_molecule
product UDP-N-acetyl-α-D-muramyl-L-Ala simple_molecule
reactant alanine simple_molecule
product phosphate simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA DdlB
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> DdlB
Description: Translation of DdlB
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> DdlB
Components:
Function Name Type
product DdlB protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
DdlB alanyl-D-alanine ala alanyl-D-alanine + phosphate
Name: ala -> alanyl-D-alanine + phosphate
Description: Reaction transforming ala into alanyl-D-alanine, phosphate
Type: state transition
Pathway Components: ala - DdlB - alanyl-D-alanine -> alanyl-D-alanine + phosphate
Components:
Function Name Type
catalyzer DdlB protein
reactant ala simple_molecule
inhibitor alanyl-D-alanine simple_molecule
product alanyl-D-alanine simple_molecule
product phosphate simple_molecule
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA FtsQ
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsQ
Description: Translation of FtsQ
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsQ
Components:
Function Name Type
product FtsQ protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA FtsA
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsA
Description: Translation of FtsA
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsA
Components:
Function Name Type
product FtsA protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA FtsZ
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsZ
Description: Translation of FtsZ
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> FtsZ
Components:
Function Name Type
product FtsZ protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA LpxC
Name: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> LpxC
Description: Translation of LpxC
Type: translation
Pathway Components: mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA -> LpxC
Components:
Function Name Type
product LpxC protein
reactant mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC_mRNA RNA
LpxC UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine Products
Name: UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine -> UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + acetate
Description: Reaction transforming UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine into UDP-3-O-(3-hydroxytetradecanoyl)glucosamine, acetate
Type: state transition
Pathway Components: UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine - LpxC -> UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + acetate
Components:
Function Name Type
catalyzer LpxC protein
reactant UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine simple_molecule
product UDP-3-O-(3-hydroxytetradecanoyl)glucosamine simple_molecule
product acetate simple_molecule
hemL_mRNA HemL
Name: hemL_mRNA -> HemL
Description: Translation of HemL
Type: translation
Pathway Components: hemL_mRNA -> HemL
Components:
Function Name Type
product HemL protein
reactant hemL_mRNA RNA
HemL glutamate 1-semialdehyde 5-aminolevulinate
Name: glutamate 1-semialdehyde -> 5-aminolevulinate
Description: Reaction transforming glutamate 1-semialdehyde into 5-aminolevulinate
Type: state transition
Pathway Components: glutamate 1-semialdehyde - HemL -> 5-aminolevulinate
Components:
Function Name Type
product 5-aminolevulinate simple_molecule
catalyzer HemL protein
reactant glutamate 1-semialdehyde simple_molecule
fecABCDE_mRNA FecA
Name: fecABCDE_mRNA -> FecA
Description: Translation of FecA
Type: translation
Pathway Components: fecABCDE_mRNA -> FecA
Components:
Function Name Type
product FecA protein
reactant fecABCDE_mRNA RNA